Reviews in Developmental Origins of Health and Disease (DOHaD)

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About this Research Topic

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Background

The early stages of life play a pivotal role in shaping an individual's health trajectory and have far-reaching implications for public health. The field of Developmental Origins of Health and Disease (DOHaD) explores how environmental exposures and experiences during fetal development and early childhood can influence long-term health outcomes. DOHaD research has illuminated the critical windows of vulnerability during prenatal and early postnatal life when exposures to various factors, such as toxins, stress, malnutrition and socio-economic conditions, can have lasting effects on health and disease risk. Understanding the biology of the developmental origins is essential for designing effective public health interventions that prioritize child health and well-being, ultimately leading to healthier populations in the future.

This Research Topic aims to explore a wide range of DOHaD-related review topics, including but not limited to:

• Review of studies investigating the impact of maternal health and pregnancy and early life-related factors on child development and long-term health outcomes.

• Review of environmental exposures and their association with childhood health conditions, including but not restricted to respiratory, neurodevelopmental, cardiovascular, and metabolic outcomes.

• Evaluation of the influence of socio-economic factors, early-life stress, and adverse childhood experiences on health disparities and lifelong health trajectories.

• Review of molecular mechanisms underlying DOHaD, shedding light on the interplay between genes and environmental factors.

• Assessment of the role of interventions and policies aimed at optimizing maternal and child health for DOHAD-based outcomes.

• Exploration of long-term follow-up studies and cohort designs to track the health of individuals from early life to adulthood.

• Evaluation of data-driven approaches and big data applications in DOHaD research to gain deeper insights into population health trends.

By bringing together studies on DOHaD research, this Research Topic aspires to provide a comprehensive overview of the field's current state, identify knowledge gaps, and propose future directions for public health initiatives focused on promoting children's well-being. We encourage authors to contribute comprehensive review articles that examine the latest advancements and research findings in DOHaD. We anticipate the research presented will promote discussion in the child health community that will translate to best practice applications in clinical, public health and policy settings.

The Reviews in Public Health Expenditure and Performance collection welcomes full-length, mini or systematic review papers.

Keywords: DOHaD, reviews, Developmental Origins of Health and Disease, environmental exposures, early childhood

Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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