The Application of High Molecular Polymers in the Treatment of Disfiguring Dermatosis

Disfiguring dermatosis is a group of inflammatory or pigmented skin diseases that occur on the face. These diseases have a long course and are difficult to cure, which affects the external image and social interaction of patients, and have a huge negative impact on their quality of life and psychology. Most disfiguring dermatoses belong to inflammatory skin diseases, and their pathogenesis often involves oxidative stress and skin barrier damage. The repair of the epidermal permeability barrier is the primary measure for the treatment of contour-damaging skin diseases. High molecular polymers exhibit excellent biocompatibility and biological inertness, ensuring minimal adverse reactions when in contact with the human body. This feature renders them suitable for diverse novel applications, including wound healing, drug delivery, and tissue engineering. Particularly in the context of disfiguring dermatosis treatment, these polymers hold immense therapeutic potential. To go beyond the traditional dermatology treatment and provide more cutting-edge therapeutic approaches for patients, we launch this Research Topic, hoping to foster innovative ideas for addressing disfiguring dermatosis.

This Research Topic aims to explore the application of high molecular polymers in the treatment of disfiguring dermatosis, optimize the therapeutic effect of patients, promote the compliance of patients and reduce the side effects of treatment. Our objective is to offer guidance in discovering novel therapeutic approaches for managing disfiguring dermatosis.

We welcome submissions of Original Research, Reviews, Mini-reviews, Case Reports, and Perspectives, with a focus on, but not limited to, the following subtopics:
● New transdermal drug delivery technologies, such as microneedles, drug-loaded microspheres, and nanocarriers.
● Facilitating targeted drug delivery and enhanced permeation by nanocarriers
● Preclinical disease or in vitro models for assessing therapeutic efficacy

Keywords: high molecular polymer, disfiguring dermatosis, wound healing, microneedle, drug-loaded microspheres, nanocarriers

Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.