Neuroenergetics in Health and Disease

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About this Research Topic

Submission deadlines

  1. Manuscript Summary Submission Deadline 31 January 2025 | Manuscript Submission Deadline 14 May 2025

  2. This Research Topic is still accepting articles.

Background

Neuroenergetics, a subfield of neuroscience, focuses on the energy dynamics within neurons and their critical role in maintaining healthy brain function. Recent studies have highlighted the importance of bioenergetics in understanding the pathophysiology of aging, neurodegenerative disorders, and traumatic brain injury. Despite significant advancements, there remain substantial gaps in our knowledge regarding the specific metabolic pathways and cellular processes that underpin neuronal energy requirements. Current research has begun to elucidate the complex interplay between energy metabolism and neuronal health, yet the precise mechanisms and their implications for disease states are not fully understood. Addressing these gaps is crucial for developing targeted therapeutic strategies to mitigate the effects of energy dysfunction in various neurological conditions.

This Research Topic aims to identify and characterize the specific metabolic pathways, cellular processes, and energy utilization patterns that support healthy neuronal function. By investigating the unique bioenergetic demands of neurons, the research seeks to uncover the vulnerabilities of these energy-intensive cells. The primary objectives include understanding how energy dysfunction contributes to aging, neurodegenerative diseases, psychiatric disorders, and traumatic brain injury. The research will test hypotheses related to alterations in neuroenergetic profiles and their role in these pathological states, ultimately aiming to identify potential therapeutic targets and strategies for intervention.

To gather further insights into the intricate relationship between neuroenergetics and neuronal health, we welcome articles addressing, but not limited to, the following themes:

- The role of bioenergetics in maintaining physiological neuronal functions
- Energy dysfunctions associated with aging, neurodegenerative disorders (such as Alzheimer's, Parkinson's, Huntington's diseases), psychiatric disorders (such as ADHD, depression, anxiety) and traumatic brain injury
- Uncovering bioenergetic demands and vulnerabilities of different neuronal cell types
- Studying alterations in neuroenergetic profiles and their role in pathological states
- Identifying potential neuroenergetic therapeutic targets and intervention strategies in neurodegenerative disorders, psychiatric disorders, and traumatic brain injury
- Understanding the relationship between energy metabolism and neurodegenerative disorders

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This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

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  • Data Report
  • Editorial
  • General Commentary
  • Hypothesis and Theory
  • Methods

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Keywords: Neuroenergetics, Brain health, Reviews, energy dysfunction, aging, neurodegeneration, traumatic brain injury

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Participating Journals

Manuscripts can be submitted to this Research Topic via the main journal or any other participating journal.

Impact

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