About this Research Topic
CircRNAs regulate immune response and participate in the occurrence and development of various immune-related diseases. CircRNAs and microRNAs have raised researchers’ interest because of their close relationship with the immune system. Emerging research indicates that circRNAs and microRNA could act as potential biomarkers related to diagnosis, therapeutic effects, and prognosis. They may also be effective therapeutic targets in immunological disorders, including rare diseases that are currently difficult to treat.
CircRNA in the immune system shows several functions, including regulating the differentiation and development of immune cells, disease response, and the occurrence and development of a series of diseases by maintaining the relative balance between pathogens and immune cells. However, the exact mechanism of circRNAs and miRNA as well as their regulatory role in immune diseases, should be further studied and explored.
This research topic aims to illuminate the emerging role of circRNAs and microRNAs in immune-related diseases. It focuses on the information of the readers regarding the biogenesis and action mechanisms, targets and clinical utility of circRNAs and microRNAs in human physiological and pathological states, with emphasis on immunological diseases.
Additionally, systems biology-based approaches to investigate circRNAs and microRNAs interaction network that influences the gene expression in the development and progression of immune diseases are welcome. The authors are encouraged to submit their original research studies concerning this topic. Review articles will also be considered.
We expect submissions based on:
• Investigating the role of circRNAs and microRNAs in immune-related diseases.
• Highlighting the possible role of circRNAs and miRNAs as regulators in immune diseases based on regulatory networks.
CircRNA in the immune system shows several functions, including regulating the differentiation and development of immune cells, disease response, and the occurrence and development of a series of diseases by maintaining the relative balance between pathogens and immune cells. However, the exact mechanism of circRNAs and miRNA as well as their regulatory role in immune diseases, should be further studied and explored.
This research topic aims to illuminate the emerging role of circRNAs and microRNAs in immune-related diseases. It focuses on the information of the readers regarding the biogenesis and action mechanisms, targets and clinical utility of circRNAs and microRNAs in human physiological and pathological states, with emphasis on immunological diseases.
Additionally, systems biology-based approaches to investigate circRNAs and microRNAs interaction network that influences the gene expression in the development and progression of immune diseases are welcome. The authors are encouraged to submit their original research studies concerning this topic. Review articles will also be considered.
We expect submissions based on:
• Investigating the role of circRNAs and microRNAs in immune-related diseases.
• Highlighting the possible role of circRNAs and miRNAs as regulators in immune diseases based on regulatory networks.
Keywords: circRNAs, miRNA, Immune diseases, Regulatory network, System Biology
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
