About this Research Topic
Microorganisms can significantly influence oral health outcomes and are responsible for causing many oral diseases, including but not limited to dental caries, periodontal diseases, oral candidiasis, mucositis, etc. The polymicrobial nature and the biofilm formation can make it extremely challenging for the management of these diseases. In addition, current available antimicrobial modalities are restricted to broad-spectrum agents, plagued by ineffectiveness, development of antimicrobial resistance, damage to the healthy oral flora, non-compliance by patients, and the associated high costs for treatment. To overcome these challenges, there is a much-needed effort towards translational research in developing more potent and selective strategies for oral infectious diseases.
This Research Topic establishes a platform for discussions on novel interventional strategies for the diagnosis, treatment, and prevention of oral microbial diseases.
It welcomes original research articles and reviews articles reporting state-of-art developments, current limitations, and future perspectives.
Addressed topics include but are not limited to:
• Novel agents for the management of oral microbial diseases and their mechanisms of action (antimicrobials, peptides, vaccines, small molecules, nanoformulations, biomaterials, natural extracts, etc.).
• Novel therapeutic/preventive approaches for precision biofilm control.
• Molecular modeling supported by physicochemical and biological testing, to identify new microbial targets for drug development.
• Artificial intelligence-based approaches for novel antimicrobial development.
• In vitro and/or in vivo pharmacology.
This Research Topic establishes a platform for discussions on novel interventional strategies for the diagnosis, treatment, and prevention of oral microbial diseases.
It welcomes original research articles and reviews articles reporting state-of-art developments, current limitations, and future perspectives.
Addressed topics include but are not limited to:
• Novel agents for the management of oral microbial diseases and their mechanisms of action (antimicrobials, peptides, vaccines, small molecules, nanoformulations, biomaterials, natural extracts, etc.).
• Novel therapeutic/preventive approaches for precision biofilm control.
• Molecular modeling supported by physicochemical and biological testing, to identify new microbial targets for drug development.
• Artificial intelligence-based approaches for novel antimicrobial development.
• In vitro and/or in vivo pharmacology.
Keywords: biofilm control, drug development, antimicrobial resistance, oral infectious disease
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
