Multiscale cancer modeling, in silico oncology, in silico psycho-oncology and digital (virtual) twins in the cancer domain

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ORIGINAL RESEARCH

Published on 24 Feb 2025

In silico oncology: a mechanistic multiscale model of clinical prostate cancer response to external radiation therapy as the core of a digital (virtual) twin. Sensitivity analysis and a clinical adaptation approach

Georgios Stamatakos
Eleni Kolokotroni
Foteini Panagiotidou
Stamatia Tsampa
Christos Kyroudis
Simon Spohn
Anca-Ligia Grosu
Dimos Baltas
Constantinos Zamboglou
Ilias Sachpazidis

doi 10.3389/fphys.2025.1434739

514 views

ORIGINAL RESEARCH

Published on 30 Oct 2024

Patient-specific prostate tumour growth simulation: a first step towards the digital twin

Ángela Pérez-Benito
José Manuel García-Aznar
María José Gómez-Benito
María Ángeles Pérez

doi 10.3389/fphys.2024.1421591

819 views

ORIGINAL RESEARCH

Published on 24 Oct 2024

Personalised in silico biomechanical modelling towards the optimisation of high dose-rate brachytherapy planning and treatment against prostate cancer

Myrianthi Hadjicharalambous
Yiannis Roussakis
George Bourantas
Eleftherios Ioannou
Karol Miller
Paul Doolan
Iosif Strouthos
Constantinos Zamboglou
Vasileios Vavourakis

Personalised in silico biomechanical modelling towards the optimisation of high dose-rate brachytherapy planning and treatment against prostate cancer

doi 10.3389/fphys.2024.1491144

579 views

REVIEW

Published on 23 Oct 2024

Towards verifiable cancer digital twins: tissue level modeling protocol for precision medicine

Sharvari Kemkar
Mengdi Tao
Alokendra Ghosh
Georgios Stamatakos
Norbert Graf
Kunal Poorey
Uma Balakrishnan
Nathaniel Trask
Ravi Radhakrishnan

Towards verifiable cancer digital twins: tissue level modeling protocol for precision medicine

doi 10.3389/fphys.2024.1473125

1,386 views

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