About this Research Topic

Background

Bioluminescence- and fluorescence-driven molecular imaging techniques have revolutionized the frontier field of chemical biology by providing molecular imaging tools to visualize molecular events supporting life phenomena in vivo and in vitro. These imaging modalities employ luminescent and fluorescent probes that emit optical readouts upon occurrence of the targeting events, enabling researchers to monitor the molecular events in vivo and in vitro. The ability to visualize molecular events within living organisms and synthetic biological systems has opened up new avenues for studying clinical/pre-clinical challenges, theragnostic, pharmaceutical goals, and even environmental issues.

This Research Topic aims to explore the applications and advancements of bioluminescence and fluorescence molecular imaging techniques in the field of chemistry and biology. By focusing on the development and utilization of luminescent and fluorescent probes, we can gain insights into the fundamental processes of life and contribute to the design of innovative diagnostic and therapeutic approaches. Recent breakthroughs in this field, such as the development of genetically encoded fluorescent proteins and bioluminescent reporters, combined with advanced microscopy techniques, have expanded the possibilities for studying biological phenomena with high sensitivity and spatial resolution.

In this Research Topic we invite submissions addressing, but not limited to, the following themes:
o Design and synthesis of luminescent and fluorescent probes for molecular imaging in chemistry.
o Development of genetically encoded reporters for studying biological processes.
o Applications of bioluminescence and fluorescence imaging in drug discovery and development.
o Studying molecular interactions and signaling pathways using imaging techniques.
o Bioassays involving bioluminescence and fluorescence
o Advancements in luminescence and fluorescence imaging technologies.
o Developments of instrumentation for improved sensitivity and resolution.

Keywords: Molecular Imaging, Bioluminescence, Fluorescence

Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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