About this Research Topic
AMR contributes to worsening the consequences of sepsis, from longer hospitalization to death. While we have relatively good data in the Western hemisphere, there is a paucity of data in other parts of the world on sepsis etiologies, though the problem is assumed to be very large, especially in low-income countries, because of limited health access and high rates of other infectious diseases.
This Research Topic has a number of aims to:
1) have an overview of AMR and sepsis, within and outside critical care with a global vision
2) provide readers with information about types of bacterial resistance, their AMR pattern, and their impact on sepsis outcomes
3) find potential solutions for the prevention of AMR spread, early diagnosis, and future initiatives on how to tackle AMR
4) discuss opportunities with regard to AMR and sepsis when there are modifiable factors
Authors could present original research articles and reviews on AMR and sepsis in and outside ICUs from high and low-income countries. We would invite authors to provide information about patterns of bacterial resistance, how we detected them, and the availability of rapid diagnostics in detecting AMR patterns. Manuscripts focusing on the on impact of good infection prevention, including device stewardship on AMR and the outcome of sepsis, are particularly encouraged. Additionally, authors could provide alternatives to antibiotics to tackle AMR and sepsis, including nanoparticles, delivered antibiotics, phage therapy, and vaccines.
Topic Editor Dr. Saeed receives research grants from Pfizer, Thermofisher Scientific, Presymptom Health, Mologic Ltd, Menarini. All other Topic Editors declare no competing interests.
Keywords: antibiotic resistance, sepsis, epidemiology, genomics, biomarkers, diagnostics, antimicrobials, antimicrobial stewardship
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