About this Research Topic
Biomaterials, as a kind of natural or synthetic functional materials, are widely applied for pharmaceutical science because of their excellent biocompatibility and biofunctions, especially playing an increasing role in controlled drug delivery. The development of biomaterials for smart drug delivery promotes advances in medicine. Various biomaterials are designed and prepared to deliver different therapeutic drugs, including small molecule drugs, peptides, proteins, genes, and so forth, to the lesion sites in a more precise and controlled manner, improve the specificity and bioavailability, upregulate the therapeutic effects of the diseases, and reduce the side effects to avoid the damage to normal tissues and organs.
Researchers are accelerating the development of controlled drug delivery, where pharmaceutical biomaterials serve as a universal platform to improve therapeutic accuracy and help us achieve an entirely "precise" drug temporally and spatially. However, many problems of biomaterials still need to be solved for intelligent drug delivery. For example, the stability, uniformity, and safety of biomaterials as drug carriers still need to be further confirmed. The biomaterials with unique drug-loading properties should be further revealed to improve the precision of targeted and controlled drug release to enhance the drug delivery system's application efficiency and meet clinical needs. The design and development of a smart library of biomaterials remain challenging, and patient heterogeneity poses an ongoing challenge. Because of this, there are many more possibilities to look forward to in biomaterial delivery drug systems. The multidisciplinary collaborations have produced innovative strategies to treat a range of diseases.
More and more scientists have spearheaded great efforts at the forefront of pharmaceutical biomaterials, motivating a wide range of biological applications, especially in controlled drug delivery, bioimaging, tissue engineering, medical device, and so on. The increasing biomedical strategies worked by scientists will significantly contribute to the next-generation precision medicine in clinics.
The research topic goal is to collect and disseminate the latest works and advancements in biomaterials for drug delivery. It generally includes the applications of biomaterials as vehicles for disease diagnosis and therapy, tissue engineering, medical devices, and so forth.
In decades, pharmaceutical biomaterials have received significant attention and have been regarded as a priority science and technology area, which has the potential to improve the current diagnostic or therapeutic systems. With the expectation and vision of precise treatment, more and more scientists have taken active parts in this interdisciplinary field, contributing to developing advanced biomaterials. The research topic provides a glimpse of state-of-the-art advances in biomaterials for drug delivery. This special issue will promote the development of biomaterials for drug delivery with more evolutionary concepts and ideas output from scientists.
This Research Topic focuses on recent advancements in biomaterials for drug delivery, including diagnostic agents, drugs, and other bioactive agents. Original Research articles, Reviews, and Mini-Reviews, but not limited to, the following topics can be included:
• Biomaterials as sensitive detectors or carriers for diagnostic agents of diseases
• Innovative biomaterials with elaborate synthesis, processing, and characterizations for drug delivery.
• Advanced smart biomaterials with sensitive bio-responsibility to specific lesion microenvironments
• Therapeutic biomaterials with various bioactivities
• Bioactive agents-incorporated biomaterials for regenerative medicine and medical devices
• Reliability and model validation of drug delivery biomaterials for clinical transformation
Researchers are accelerating the development of controlled drug delivery, where pharmaceutical biomaterials serve as a universal platform to improve therapeutic accuracy and help us achieve an entirely "precise" drug temporally and spatially. However, many problems of biomaterials still need to be solved for intelligent drug delivery. For example, the stability, uniformity, and safety of biomaterials as drug carriers still need to be further confirmed. The biomaterials with unique drug-loading properties should be further revealed to improve the precision of targeted and controlled drug release to enhance the drug delivery system's application efficiency and meet clinical needs. The design and development of a smart library of biomaterials remain challenging, and patient heterogeneity poses an ongoing challenge. Because of this, there are many more possibilities to look forward to in biomaterial delivery drug systems. The multidisciplinary collaborations have produced innovative strategies to treat a range of diseases.
More and more scientists have spearheaded great efforts at the forefront of pharmaceutical biomaterials, motivating a wide range of biological applications, especially in controlled drug delivery, bioimaging, tissue engineering, medical device, and so on. The increasing biomedical strategies worked by scientists will significantly contribute to the next-generation precision medicine in clinics.
The research topic goal is to collect and disseminate the latest works and advancements in biomaterials for drug delivery. It generally includes the applications of biomaterials as vehicles for disease diagnosis and therapy, tissue engineering, medical devices, and so forth.
In decades, pharmaceutical biomaterials have received significant attention and have been regarded as a priority science and technology area, which has the potential to improve the current diagnostic or therapeutic systems. With the expectation and vision of precise treatment, more and more scientists have taken active parts in this interdisciplinary field, contributing to developing advanced biomaterials. The research topic provides a glimpse of state-of-the-art advances in biomaterials for drug delivery. This special issue will promote the development of biomaterials for drug delivery with more evolutionary concepts and ideas output from scientists.
This Research Topic focuses on recent advancements in biomaterials for drug delivery, including diagnostic agents, drugs, and other bioactive agents. Original Research articles, Reviews, and Mini-Reviews, but not limited to, the following topics can be included:
• Biomaterials as sensitive detectors or carriers for diagnostic agents of diseases
• Innovative biomaterials with elaborate synthesis, processing, and characterizations for drug delivery.
• Advanced smart biomaterials with sensitive bio-responsibility to specific lesion microenvironments
• Therapeutic biomaterials with various bioactivities
• Bioactive agents-incorporated biomaterials for regenerative medicine and medical devices
• Reliability and model validation of drug delivery biomaterials for clinical transformation
Keywords: biomaterial, pharmaceutical, controlled drug loading and release, improved efficacy, decreased side effect
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