About this Research Topic
This themed issue will cover more than 10 articles (research papers, review, perspectives, editorial etc.) from leading experts in bio-imaging, nanotheranostics, nanomedicines, drug delivery, combination therapeutics, biomaterials etc. and will be beneficial for young researchers to understand the clinical translational challenges and their new scopes. Next, nanotheranostics have potential implications for site-selective imaging and cancer therapy in pre-clinical and clinical models. So far, various nanotheranostics systems have been proposed for pre-clinical studies especially for solid tumor imaging and therapeutics. These nanotheranostics are considered versatile platforms for early-stage diagnosis and therapeutics with better efficacy at a minimum dose owing to their integration of multiple agents in single system at nanoscale. However, the clinical translational progress is slow may be due to poor understanding on their engineering or testing interventions. An exciting frontier space of nanotheranostics is developing interventional methodologies. Engineering integrated diagnostics, therapeutics and targeting agents in a single platform at nanoscale without compromising individual’s efficacy result in clinically acceptable systems/medicines. Together, nanotheranostics and nanomedicines research area facilitate new levels of developing safe medicines which can get FDA’s attention for further trials and approval. Nanotheranostics can resolve major concerns of health issues along with biosafety and sustainability
Importantly, nanotheranostics have been widely explored due to low diagnostics costs, better therapeutic efficacy and decreased hospital stay. Hence, the global market for nanotheranostics is anticipated to be more than $187 billion. However, the current translation of nanotheranostics into clinical practice is still a path strewn with incredible obstacles. Intervention in engineering nanotheranostics or their diagnostic and therapeutic approaches can resolve their clinical translation. Hence, this themed issue would offer a joint platform for biomedical researchers, oncologists, radiologists, and the entire nanomedicine community to share their knowledge and build a bridge between medical doctors, biomedical scientists and pharmaceutical industries.
Keywords: Nanotheranostics, Imaging, Therapeutics, Drug Delivery, Multifunctional Hybrid Systems, Molecular Engineering, Precision Medicine, Ultrabright nanomedicine, Bio- engineering
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