About this Research Topic
Peripheral blood immune monitoring of cancer therapy is a crucial aspect of assessing the immune response and evaluating the efficacy of cancer treatments. However, there are several challenges associated with this process: heterogeneity of the immune system, dynamic nature of the immune response, lack of standardized assays and protocols, low frequency of immune cells, tumor heterogeneity and antigen escape, overlapping effects of systemic therapies, need for expertise and sophisticated data analysis and interpretation of complex datasets.
Beyond the traditional immune cell subsets, like T cells and B cells, new innate, innate-like and unconventional immune cells gathered the attention of immunologists, cancer researchers and oncologists, recently.
This new Research Topic aims at understanding the dynamics and functional properties of immune cells in peripheral blood before and after immunotherapy administration that can help to assess their potential as biomarkers of treatment response and identify targets for therapeutic interventions.
We encourage the submission of original research and review articles on the cellular and molecular mechanisms of peripheral immune cells in cancer therapy.
IMPORTANT NOTE: Bioinformatics-only manuscripts or computational analyses of public genomic or transcriptomic databases without any form of validation (such as an independent cohort study or biological validation in vitro or in vivo) are outside the scope of this section and will not be considered for inclusion in this Research Topic.
Beyond the traditional immune cell subsets, like T cells and B cells, new innate, innate-like and unconventional immune cells gathered the attention of immunologists, cancer researchers and oncologists, recently.
This new Research Topic aims at understanding the dynamics and functional properties of immune cells in peripheral blood before and after immunotherapy administration that can help to assess their potential as biomarkers of treatment response and identify targets for therapeutic interventions.
We encourage the submission of original research and review articles on the cellular and molecular mechanisms of peripheral immune cells in cancer therapy.
IMPORTANT NOTE: Bioinformatics-only manuscripts or computational analyses of public genomic or transcriptomic databases without any form of validation (such as an independent cohort study or biological validation in vitro or in vivo) are outside the scope of this section and will not be considered for inclusion in this Research Topic.
Keywords: Peripheral Blood, Immune Cells, Monitoring, Cancer Therapy
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
