About this Research Topic
Cancer is still one of the leading causes of death in the world population. Epidemiological data states that there were 10,000,000 deaths from cancer around the world in 2020. To this data, already dramatic in itself, we must add the data related to the socio-economic impact. In fact, both medical expenses and non-medical expenses such as domestic help, transport, hotel expenses, and special diets are constantly increasing. Furthermore, these calculations must also include the loss of income from the work of patients and relatives and the expenses borne by public health agencies. Most modern therapeutic protocols adopted do not seem to be able to significantly improve the results in terms of prognosis and survival for particular types of cancer. Furthermore, in applying these protocols, there are considerable criticalities linked, for example, to the toxicity of chemotherapy drugs, to the toxicity linked to radiotherapy, and to the complications linked to surgical treatments.
Recently, the advent of nanotechnologies has sparked new and concrete hopes in the formulation of more effective therapeutic strategies. Nanotechnology may be an optimal strategy to overcome these limitations and, at the same time, stimulate the production of a wide set of nanoplatforms with multifunctional abilities for tumor targeting, drug loading, and controlled release.
Currently, a complete evaluation of the size, shape, composition, and aggregation-dependent interactions of nanomaterials with biological systems is lacking, and thus it is unclear whether the exposure of humans to engineered nanostructures could produce harmful biological responses. The same characteristics that make nanomaterials so attractive may contribute to the toxicological profile of nanomaterials in biological systems. Nanoparticles have electronic, optical, and magnetic properties that are related to their physical dimensions, and their breakdown could lead to a unique toxic effect that is difficult to predict.
This Research Topic aims to highlight recent developments in the development and application of Cancer Nanoformulations and welcomes submissions including, but not limited to:
-Nanomedicine in anticancer drug/nucleotide/protein delivery
-Utilization of nanomedicine for assessment of treatment responses
- Development of cancer vaccines
- Advancement of cancer immunotherapy
- Advantages of nanomaterials in cancer medicine
- Novel therapeutic and imaging modalities offered by nanomaterials
- Enhancing tumor penetration and targeting via nanomaterial solutions
Recently, the advent of nanotechnologies has sparked new and concrete hopes in the formulation of more effective therapeutic strategies. Nanotechnology may be an optimal strategy to overcome these limitations and, at the same time, stimulate the production of a wide set of nanoplatforms with multifunctional abilities for tumor targeting, drug loading, and controlled release.
Currently, a complete evaluation of the size, shape, composition, and aggregation-dependent interactions of nanomaterials with biological systems is lacking, and thus it is unclear whether the exposure of humans to engineered nanostructures could produce harmful biological responses. The same characteristics that make nanomaterials so attractive may contribute to the toxicological profile of nanomaterials in biological systems. Nanoparticles have electronic, optical, and magnetic properties that are related to their physical dimensions, and their breakdown could lead to a unique toxic effect that is difficult to predict.
This Research Topic aims to highlight recent developments in the development and application of Cancer Nanoformulations and welcomes submissions including, but not limited to:
-Nanomedicine in anticancer drug/nucleotide/protein delivery
-Utilization of nanomedicine for assessment of treatment responses
- Development of cancer vaccines
- Advancement of cancer immunotherapy
- Advantages of nanomaterials in cancer medicine
- Novel therapeutic and imaging modalities offered by nanomaterials
- Enhancing tumor penetration and targeting via nanomaterial solutions
Keywords: Cancer Nanoformulations, Immunotherapy, Tumor Targeting, Toxicology, Nanomedicine
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
