As we age, our ability to focus on nearby objects gradually diminishes, a condition known as presbyopia. Presbyopia is mainly caused by the natural hardening and/or continuous growth of the lens with age, which affects its ability to accommodate. This problem affects many individuals worldwide, with an ...
As we age, our ability to focus on nearby objects gradually diminishes, a condition known as presbyopia. Presbyopia is mainly caused by the natural hardening and/or continuous growth of the lens with age, which affects its ability to accommodate. This problem affects many individuals worldwide, with an estimated 1.8 billion people experiencing it in 2015. Unfortunately, many of these people do not have adequate vision correction, leading to visual impairment, resulting in reduced productivity and a lower quality of life. Recent research has discovered methods to ease presbyopia temporarily. However, additional research on the biochemical and biomechanical aspects of the lens is required to develop treatments that can reverse or prevent presbyopia.
This special issue features research and review articles by leading scientists on lens stiffness, accommodation, and presbyopia. The topics to be covered:
• Post-translational modifications of lens proteins and capsule: relation to lens aging
• Interaction of lens epithelial cells with capsule: Effect of aging
• Lens transport systems in aging
• Lens cytoskeletal proteins and aging
• Biomechanical properties of the lens and lens capsule: effect of aging
• Techniques to measure lens stiffness and accommodation
• Therapies to reverse/prevent lens stiffness
• Driving forces for lens growth
Keywords:
Lens stiffness, accommodation, presbyopia
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.