About this Research Topic
Cancer is undoubtedly a major health problem and one of the leading contributors to the global disease burden. Cancer is among the primary causes of death worldwide, and, despite the prominent cancer research and development of multi-targeted therapeutic options, death rates from cancer are still dramatically high. Recent evidence suggests cancer research is now at a critical crossroads. New data and fresh concepts are transforming traditional views on biology, tumorigenesis, and therapeutic interventions. Current data suggests that in the next ten years, approximately 22 million new cancer cases and 13 million cancer-related deaths are expected worldwide. The care of patients with cancer has remained dramatically unchanged for many years, and the development of novel anticancer drugs remains a challenging concept. With that, the FDA approves a very small number of novel anticancer drugs every year. Today, there is increased scientific interest in drug repurposing, which could provide affordable treatments to patients. Drug repurposing for cancer treatment is associated with lower costs and may represent a significant ‘tool’ for anticancer therapy.
With this Research Topic, we aim to provide a discussion forum on the current status of drug repurposing for cancer treatment towards new discoveries.
We welcome Original Research, Reviews, Mini Reviews, Opinions, Perspectives, and Systematic Reviews focusing on drug repurposing for several cancers treatment, whereas brain tumors and gastrointestinal tumors are of high interest, but not limited to drug repurposing acting on:
- Metastasis process blocking
- Therapy resistance
- Blocking of tumorigenesis processes
Please note: manuscripts consisting solely of bioinformatics or computational analysis of public genomic or transcriptomic databases which are not accompanied by validation (independent cohort or biological validation in vitro or in vivo) are out of scope for this section and will not be accepted as part of this Research Topic.
With this Research Topic, we aim to provide a discussion forum on the current status of drug repurposing for cancer treatment towards new discoveries.
We welcome Original Research, Reviews, Mini Reviews, Opinions, Perspectives, and Systematic Reviews focusing on drug repurposing for several cancers treatment, whereas brain tumors and gastrointestinal tumors are of high interest, but not limited to drug repurposing acting on:
- Metastasis process blocking
- Therapy resistance
- Blocking of tumorigenesis processes
Please note: manuscripts consisting solely of bioinformatics or computational analysis of public genomic or transcriptomic databases which are not accompanied by validation (independent cohort or biological validation in vitro or in vivo) are out of scope for this section and will not be accepted as part of this Research Topic.
Keywords: brain tumors, gastrointestinal cancer, targeted drug discovery, cancer therapeutics, drug repurposing, metastasis, tumorigenesis
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
