About this Research Topic
The goal of this Research Topic is to use more direct and efficient means to find small molecule lead compounds with anticancer activity. The direct targets of small molecule compounds can be found by target recognition technology, and the mechanism of action can be elucidated. At the same time, novel small-molecule lead compounds can also catch more potential anticancer targets and mechanisms. It can provide more possibilities for the discovery of new anticancer drugs. The topics we are interested in covering include:
1. New technology and application of guided separation of anticancer active compounds.
2. Anticancer targets and mechanisms of natural anticancer products and their structural modifiers.
3. Discovery of novel anticancer lead compounds with novel structures.
4. Application of target recognition technology in the determination of direct target of natural anticancer products.
Please note: manuscripts consisting solely of bioinformatics or computational analysis of public genomic or transcriptomic databases which are not accompanied by validation (independent cohort or biological validation in vitro or in vivo) are out of scope for this section and will not be accepted as part of this Research Topic.
Keywords: Anticancer Natural Products, Leading Compound, Bioactivity-guided Isolation, Potential Cancer Targets, Target Recognition Technology
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.