About this Research Topic
This Research Topic is focused on the signals in programmed cell death and their crosstalk. The aim is to provide a comprehensive overview of the current knowledge regarding the regulation of signaling pathways involved in different types of programmed cell death, and how they interplay. It also aims to highlight the important molecular mechanisms that govern programmed cell death, and how their crosstalk influences the pathogenesis of different diseases. Lastly, the Research Topic aims to provide an update on emerging therapeutic strategies targeting programmed cell death and their signaling pathways.
Topics that papers are expected to cover:
• Molecular mechanisms of PCD
• Crosstalk between apoptosis, necroptosis, and autophagy
• Signaling pathways involved in programmed cell death
• Role of non-coding RNAs in programmed cell death
• The role of the inflammasome in programmed cell death
• Crosstalk between programmed cell death and immunity
• Role of programmed cell death and their crosstalk in cancer, neurodegeneration, and autoimmune disorders
• Emerging therapeutic strategies targeting programmed cell death and their signaling pathways
Keywords: Apoptosis, Necroptosis, Autophagy, Inflammasome, Immunity, Cancer, Neurodegeneration, Autoimmune disorders
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.