About this Research Topic
Depression is a complex mental disorder that affects millions of people worldwide. Despite the availability of treatments, many individuals with depression continue to experience significant impairment in their daily lives. Recent research has identified several molecular mechanisms that contribute to the development and progression of depression, including changes in neurotransmitter levels, alterations in cellular signaling pathways, and abnormalities in brain structure and function.
This Research Topic aims to bring together cutting-edge research on the molecular mechanisms of depression from a variety of disciplines, including genetics, neurobiology, and pharmacology. We invite Original Research articles, Reviews, and Perspectives that cover the following topics:
- The genetic basis of depression: recent advances in identifying genetic risk factors for depression
- The role of neurotransmitters in depression: the role of serotonin, norepinephrine, and other neurotransmitters in the pathophysiology of depression
- Cellular signaling pathways in depression: the role of intracellular signaling pathways, such as the cyclic AMP signaling pathway, in the development and progression of depression
- Brain imaging studies of depression: recent advances in identifying brain regions involved in depression
- Emerging therapies for depression: novel therapeutic targets and approaches for the treatment of depression
We particularly encourage submissions that explore new avenues for the development of targeted therapies for depression, and that highlight the translational potential of research on the molecular mechanisms of the disorder.
With this Research Topic, we aim to provide a comprehensive overview of the current state of research on the molecular mechanisms of depression, and to highlight new directions for future research.
This Research Topic aims to bring together cutting-edge research on the molecular mechanisms of depression from a variety of disciplines, including genetics, neurobiology, and pharmacology. We invite Original Research articles, Reviews, and Perspectives that cover the following topics:
- The genetic basis of depression: recent advances in identifying genetic risk factors for depression
- The role of neurotransmitters in depression: the role of serotonin, norepinephrine, and other neurotransmitters in the pathophysiology of depression
- Cellular signaling pathways in depression: the role of intracellular signaling pathways, such as the cyclic AMP signaling pathway, in the development and progression of depression
- Brain imaging studies of depression: recent advances in identifying brain regions involved in depression
- Emerging therapies for depression: novel therapeutic targets and approaches for the treatment of depression
We particularly encourage submissions that explore new avenues for the development of targeted therapies for depression, and that highlight the translational potential of research on the molecular mechanisms of the disorder.
With this Research Topic, we aim to provide a comprehensive overview of the current state of research on the molecular mechanisms of depression, and to highlight new directions for future research.
Keywords: molecular, depression, molecular mechanisms
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
