A vast majority about bacterial pathogenesis is based on laboratory model studies that by nature are simplified and do not incorporate the complex environment in the human host. With recent improvements in RNA sequencing technologies and the increased availability of those methods, studies reporting on the human transcriptome in various clinical settings are common. However, studies on the bacterial transcriptomic in clinical samples or at the site of infection are still few. We anticipate that such studies will become increasingly common and yield important information about how bacteria persist and cause disease in the human host.
We would like to increase the awareness of the research topic and stimulate to more studies that are based on this technology.
Themes: Proof of concept and clinical research based on the transcriptome of bacterial pathogens infecting humans.
Research questions can include clinical variables (survival, severity of disease, specific symptoms or complications) or bacterial variables (regulation, metabolism, virulence factors or antibiotic resistance).
Types of manuscript: Original articles or short reports with original data
Keywords:
RNA-sequencing, in vivo transcriptomics, clinical samples, infections, gene expression, bacterial pathogenesis
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
A vast majority about bacterial pathogenesis is based on laboratory model studies that by nature are simplified and do not incorporate the complex environment in the human host. With recent improvements in RNA sequencing technologies and the increased availability of those methods, studies reporting on the human transcriptome in various clinical settings are common. However, studies on the bacterial transcriptomic in clinical samples or at the site of infection are still few. We anticipate that such studies will become increasingly common and yield important information about how bacteria persist and cause disease in the human host.
We would like to increase the awareness of the research topic and stimulate to more studies that are based on this technology.
Themes: Proof of concept and clinical research based on the transcriptome of bacterial pathogens infecting humans.
Research questions can include clinical variables (survival, severity of disease, specific symptoms or complications) or bacterial variables (regulation, metabolism, virulence factors or antibiotic resistance).
Types of manuscript: Original articles or short reports with original data
Keywords:
RNA-sequencing, in vivo transcriptomics, clinical samples, infections, gene expression, bacterial pathogenesis
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.