About this Research Topic
Fever is defined as the rise or increase in body temperature above the normal range in response to an illness. It is an integral part of an overall response from the body's immune system to counter an abnormal process occurring in the body. There are many patterns of fever considering its timeline. This Research Topic focuses on recurrent fever in children.
Recurrent fever is to be distinguished from temporary or continuous fever. It has a cyclic pattern interspersed with periods of normal body temperature which can be so orderly to the point of being periodic. This pattern can be a manifestation of an underlying illness, unmasking its presence, whether a disease, a syndrome, or a disorder. The list includes auto-inflammatory diseases, immune deficiency diseases, autoimmune diseases, infections, hematological and oncological diseases as well as lysosomal storage diseases.
Consequently, awareness of this possibility is imperative so as not to miss this constellation of underlying possibilities.
Also, the list and expression of this group in pediatrics will be different from what is encountered in the adult population.
This Research Topic aims to shed light on this group of illnesses in pediatrics, increasing the awareness of care providers which reflects in better understanding and diagnosis. Another objective is to provide a brief manual for the best management based on the available guidelines, recommendations, and expert opinion.
We welcome original research, reviews, mini-reviews, and meta-analyses that;
1. Appreciate the importance of early detection of the phenomenon and the possible underlying causes.
2. Provide an expansive list of causes including common as well as rare causes so as not to be missed in the differential diagnosis.
3. Emphasize the importance of a multidisciplinary approach in dealing with this group that includes clinicians, geneticists, laboratory experts, pathologists, radiologists…..etc
4. Provide a manual on how to manage the underlying cause and, naturally the fever within its context.
Recurrent fever is to be distinguished from temporary or continuous fever. It has a cyclic pattern interspersed with periods of normal body temperature which can be so orderly to the point of being periodic. This pattern can be a manifestation of an underlying illness, unmasking its presence, whether a disease, a syndrome, or a disorder. The list includes auto-inflammatory diseases, immune deficiency diseases, autoimmune diseases, infections, hematological and oncological diseases as well as lysosomal storage diseases.
Consequently, awareness of this possibility is imperative so as not to miss this constellation of underlying possibilities.
Also, the list and expression of this group in pediatrics will be different from what is encountered in the adult population.
This Research Topic aims to shed light on this group of illnesses in pediatrics, increasing the awareness of care providers which reflects in better understanding and diagnosis. Another objective is to provide a brief manual for the best management based on the available guidelines, recommendations, and expert opinion.
We welcome original research, reviews, mini-reviews, and meta-analyses that;
1. Appreciate the importance of early detection of the phenomenon and the possible underlying causes.
2. Provide an expansive list of causes including common as well as rare causes so as not to be missed in the differential diagnosis.
3. Emphasize the importance of a multidisciplinary approach in dealing with this group that includes clinicians, geneticists, laboratory experts, pathologists, radiologists…..etc
4. Provide a manual on how to manage the underlying cause and, naturally the fever within its context.
Keywords: recurrent fever in pediatrics, auto-inflammatory diseases, autoimmune diseases, immune deficiency, infections
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
