About this Research Topic
Many viruses have evolved to meet this challenge by using their small genomic RNA in a multifunctional way: the RNA contains both the encoded genetic information and the structural signals that are required to interact with and manipulate host cell machinery. The impact of these structural motifs is highlighted by the critical functions contained in structured RNA elements, including the recruitment and manipulation of host cell factors, and the regulation of processes necessary for viral replication.
The biological relevance of these RNA motifs is evident in their high degree of structural conservation. In this research topic we welcome submissions of experts in the field to review a variety of functionally critical RNA structural features found in RNA viruses. The examples proposed in this Research Topic will allow the reader to gain a foundation of knowledge in regard to the diversity of structural motifs controlling RNA virus multiplication, as well as the current methods being used to study these RNAs. We encourage authors to comment not only on the current understanding of the relevant motif, but also on the open questions in knowledge that are likely to drive further experiments aimed at understanding these important RNA viruses.
Keywords: RNA virus, regulatory motifs, RNA structure, RNA-binding proteins, emerging diseases
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.