Frontiers | Tuberculosis diagnosis, drug resistance, and drug target discovery

Tuberculosis diagnosis, drug resistance, and drug target discovery

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ORIGINAL RESEARCH

Published on 08 Jan 2025

Analyses of blood-derived host biomarkers for pulmonary tuberculosis diagnosis in human immunodeficiency virus co-infected individuals in sub-Saharan Africa: a systematic review and meta-analysis

Antony M. Rapulana
Thabo Mpotje
Nondumiso Mthiyane
Theresa K. Smit
Timothy D. McHugh
Mohlopheni J. Marakalala

doi 10.3389/ftubr.2024.1377540

228 views

ORIGINAL RESEARCH

Published on 14 Nov 2024

Reduced bacillary load in elderly patients with active extrapulmonary and pulmonary tuberculosis in Peru: analysis of confirmatory culture after acid-fast bacilli test

Jeel Moya-Salazar
Jonathan Samán
Israel A. Pasco
Marcia M. Moya-Salazar
Víctor Rojas-Zumaran
Hans Contreras-Pulache

doi 10.3389/fmicb.2024.1398999

384 views

ORIGINAL RESEARCH

Published on 31 Jul 2024

Toxin-antitoxin system gene mutations driving Mycobacterium tuberculosis transmission revealed by whole genome sequencing

Yawei Hou
Yifan Li
Ningning Tao
Xianglong Kong
Yameng Li
Yao Liu
Huaichen Li
Zhenguo Wang

doi 10.3389/fmicb.2024.1398886

1,336 views

ORIGINAL RESEARCH

Published on 03 Jul 2024

Nanopore-based targeted next-generation sequencing of tissue samples for tuberculosis diagnosis

Weiwei Gao
Chen Yang
Tianzhen Wang
Yicheng Guo
Yi Zeng

doi 10.3389/fmicb.2024.1403619

1,704 views

ORIGINAL RESEARCH

Published on 14 Jun 2024

Development and evaluation of a triplex droplet digital PCR method for differentiation of M. tuberculosis, M. bovis and BCG

Yao Qu
Mengda Liu
Xiangxiang Sun
Yongxia Liu
Jianzhu Liu
Liping Hu
Zhiqiang Jiang
Fei Qi
Wenlong Nan
6 more
Xiaoxu Fan

doi 10.3389/fmicb.2024.1397792

1,558 views

ORIGINAL RESEARCH

Published on 30 May 2024

Individualized lipid profile in urine-derived extracellular vesicles from clinical patients with Mycobacterium tuberculosis infections

Lingna Lyu
Hongyan Jia
Qiuyue Liu
Wenxia Ma
Zihui Li
Liping Pan
Xiuli Zhang

doi 10.3389/fmicb.2024.1409552

1,042 views

ORIGINAL RESEARCH

Published on 17 May 2024

Disease spectrum and prognostic factors in patients treated for tuberculous meningitis in Shaanxi province, China

Ting Wang
Meng-yan Li
Xin-shan Cai
Qiu-sheng Cheng
Ze Li
Ting-ting Liu
Lin-fu Zhou
Hong-hao Wang
Guo-dong Feng
1 more
Gang Zhao

doi 10.3389/fmicb.2024.1374458

1,111 views

ORIGINAL RESEARCH

Published on 10 May 2024

Evaluation of a real-time PCR assay performance to detect Mycobacterium tuberculosis, rifampicin, and isoniazid resistance in sputum specimens: a multicenter study in two major cities of Indonesia

Ida Parwati
Lidya Chaidir
Muhammad Yunus
Maya Marinda Montain
Dini Budhiarko
Siti Fatimah Selasih
Ryan Bayusantika Ristandi
Rifky Waluyajati Rachman
Raden Desy Nurhayati
1 more
Akterono Dwi Budiyati

doi 10.3389/fmicb.2024.1372647

2,230 views

ORIGINAL RESEARCH

Published on 25 Mar 2024

Deletion of the Mycobacterium tuberculosis cyp138 gene leads to changes in membrane-related lipid composition and antibiotic susceptibility

Yun Lu
Hongtong Chen
Zhiyuan Shao
Lang Sun
Congran Li
Yu Lu
Xuefu You
Xinyi Yang

doi 10.3389/fmicb.2024.1301204

3,589 views
2 citations

SYSTEMATIC REVIEW

Published on 11 Mar 2024

Diagnostic accuracy of oral swab for detection of pulmonary tuberculosis: a systematic review and meta-analysis

Fuzhen Zhang
Yilin Wang
Xuxia Zhang
Kewei Liu
Yuanyuan Shang
Wei Wang
Yuanyuan Liu
Liang Li
Yu Pang

doi 10.3389/fmed.2023.1278716

1,935 views

ORIGINAL RESEARCH

Published on 20 Feb 2024

Advancements in LAM-based diagnostic kit for tuberculosis detection: enhancing TB diagnosis in HIV-negative individuals

Man Gao
Qianhong Wu
Xinhong Wang
Xiuli Sun
Meng Li
Guanghong Bai

doi 10.3389/fmicb.2024.1367092

3,400 views
1 citation

ORIGINAL RESEARCH

Published on 08 Feb 2024

The incremental value of Mycobacterium tuberculosis trace nucleic acid detection in CT-guided percutaneous biopsy needle rinse solutions for the diagnosis of tuberculosis

Zihui Li
Bing Wang
Boping Du
Qi Sun
Dongpo Wang
Rongrong Wei
Chenghai Li
Chuanzhi Zhu
Hongyan Jia
3 more
Dailun Hou

doi 10.3389/fmicb.2024.1335526

760 views
1 citation

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Articles

Analyses of blood-derived host biomarkers for pulmonary tuberculosis diagnosis in human immunodeficiency virus co-infected individuals in sub-Saharan Africa: a systematic review and meta-analysis

Reduced bacillary load in elderly patients with active extrapulmonary and pulmonary tuberculosis in Peru: analysis of confirmatory culture after acid-fast bacilli test

Toxin-antitoxin system gene mutations driving Mycobacterium tuberculosis transmission revealed by whole genome sequencing

Nanopore-based targeted next-generation sequencing of tissue samples for tuberculosis diagnosis

Development and evaluation of a triplex droplet digital PCR method for differentiation of M. tuberculosis, M. bovis and BCG

Individualized lipid profile in urine-derived extracellular vesicles from clinical patients with Mycobacterium tuberculosis infections

Disease spectrum and prognostic factors in patients treated for tuberculous meningitis in Shaanxi province, China

Evaluation of a real-time PCR assay performance to detect Mycobacterium tuberculosis, rifampicin, and isoniazid resistance in sputum specimens: a multicenter study in two major cities of Indonesia

Deletion of the Mycobacterium tuberculosis cyp138 gene leads to changes in membrane-related lipid composition and antibiotic susceptibility

Diagnostic accuracy of oral swab for detection of pulmonary tuberculosis: a systematic review and meta-analysis

Advancements in LAM-based diagnostic kit for tuberculosis detection: enhancing TB diagnosis in HIV-negative individuals

The incremental value of Mycobacterium tuberculosis trace nucleic acid detection in CT-guided percutaneous biopsy needle rinse solutions for the diagnosis of tuberculosis

Frontiers in Microbiology

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