About this Research Topic
In the dynamic realm of gerontological research, a profound exploration into the intricate biological underpinnings of aging has unveiled groundbreaking insights. Among these, the concept of "inflammaging" stands out, encapsulating the persistent, subtle inflammatory state intrinsic to the aging continuum. This Issue will be dedicated to unraveling the sophisticated matrix of biological processes that underpin inflammaging and its pivotal contribution to the pathology of age-related conditions. By delving into the reciprocal interactions among cellular aging, immune system decline, and biochemical signaling cascades, our goal is to spotlight emergent therapeutic horizons and avenues for intervention. The advent of senolytic agents, anti-inflammatory tactics, and immune modulation therapies heralds a new era of potential for ameliorating the deleterious effects of inflammaging and its pathological outcomes. Through the amalgamation of forefront research endeavours, this research submission call-for seeks to orchestrate a nuanced synthesis of contemporary findings and mechanistic elucidations concerning inflammaging, underscoring its pivotal influence on the spectrum of age-associated diseases.
In this Research Topic, we would like to encompass a broad spectrum of discussions on inflammaging, with a particular emphasis on mechanistic insights, therapeutic targets, and intervention methodologies. Contributions that probe into the creation of innovative therapies, spanning senolytics, immune modulators, and anti-inflammatory agents, as well as studies evaluating lifestyle interventions and their effects on inflammaging, are especially encouraged for this edition. We extend an invitation to scholars to contribute their expertise on topics including, but not limited to, cellular aging, immune system aging, molecular underpinnings, signaling pathways, biomarkers, and the resolution of inflammation. Submissions of original research, comprehensive reviews, meta-analyses, and methodological innovations pertaining to inflammaging are warmly welcomed.
In this Research Topic, we would like to encompass a broad spectrum of discussions on inflammaging, with a particular emphasis on mechanistic insights, therapeutic targets, and intervention methodologies. Contributions that probe into the creation of innovative therapies, spanning senolytics, immune modulators, and anti-inflammatory agents, as well as studies evaluating lifestyle interventions and their effects on inflammaging, are especially encouraged for this edition. We extend an invitation to scholars to contribute their expertise on topics including, but not limited to, cellular aging, immune system aging, molecular underpinnings, signaling pathways, biomarkers, and the resolution of inflammation. Submissions of original research, comprehensive reviews, meta-analyses, and methodological innovations pertaining to inflammaging are warmly welcomed.
Keywords: Inflammaging, Chronic inflammation, Aging process, Senescence, Age-related diseases
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
