About this Research Topic
Coronary microvascular dysfunction (CMD) covers a wide range of clinical situations where the structure and function of coronary microcirculation are affected. The established structural mechanisms include internal arteriolar remodeling, vascular thinning and microembolization after atherosclerotic plaque rupture or during coronary intervention. The existing techniques for evaluating CMD mainly include positron emission tomography, myocardial contrast echocardiography, cardiac CT, cardiac magnetic resonance imaging (CMR), X-ray coronary angiography, and Doppler blood flow wire.
CMR is a "gold standard" imaging examination method for evaluating the structure and function of the heart. It can accurately measure left ventricular mass and function, distinguish myocardial tissue composition characteristics, and detect myocardial metabolic substances with magnetic resonance spectroscopy (MRS). In addition, new technologies have been continuously introduced in recent years, including ventricular wall strain, T1, T2, T2 * mapping, and extracellular volume, bringing opportunities for us to identify CMD risk factors, pathogenesis, and abnormal display. As the subject area keeps evolving, it is possible for us to make breakthrough progresses.
In this research topic, we want to create a forum based on CMR for early identification, risk stratification and prognosis evaluation of CMD. We welcome submissions on the following topics, but are not limited to:
- The performance of CMR for CMD
- CMR tests for CMD and outcomes
- CMR test for CMD: sex and ethnic differences
- CMD changes in cardiomyopathies on CMR (hypertrophic cardiomyopathy, aortic stenosis, Fabry disease, dilated cardiomyopathy, diabetic cardiomyopathy)
- New application of CMR for CMD: going beyond visual assessment
- Techniques for automatic quantification of CMD (e.g., machine learning)
CMR is a "gold standard" imaging examination method for evaluating the structure and function of the heart. It can accurately measure left ventricular mass and function, distinguish myocardial tissue composition characteristics, and detect myocardial metabolic substances with magnetic resonance spectroscopy (MRS). In addition, new technologies have been continuously introduced in recent years, including ventricular wall strain, T1, T2, T2 * mapping, and extracellular volume, bringing opportunities for us to identify CMD risk factors, pathogenesis, and abnormal display. As the subject area keeps evolving, it is possible for us to make breakthrough progresses.
In this research topic, we want to create a forum based on CMR for early identification, risk stratification and prognosis evaluation of CMD. We welcome submissions on the following topics, but are not limited to:
- The performance of CMR for CMD
- CMR tests for CMD and outcomes
- CMR test for CMD: sex and ethnic differences
- CMD changes in cardiomyopathies on CMR (hypertrophic cardiomyopathy, aortic stenosis, Fabry disease, dilated cardiomyopathy, diabetic cardiomyopathy)
- New application of CMR for CMD: going beyond visual assessment
- Techniques for automatic quantification of CMD (e.g., machine learning)
Keywords: coronary microvascular dysfunction, cardiovascular imaging, cardiac remodelling, cardiac function, myocardial ischemia
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
