About this Research Topic
The goal of this Research Topic is to raise a discussion on the advances in molecular and pharmacological mechanisms of novel targeted therapies for melanoma aiming for high efficacy and minimum side effects. We hope to receive promising results about new or repositioned drugs and elucidate the mechanisms and molecular targets of such therapies in melanoma management and its metastasis.
Therefore, this Research Topic is open to Scope Review, Systematic Review with or without Meta-Analysis, Mini-Review, Clinical Trial, and Original Research articles focusing on understanding the molecular and pharmacological mechanisms of novel targeted therapies for melanoma. Studies dealing with the identification and molecular signaling of pathways related to melanoma progression, and potential treatments are welcome. Of particular interest, immunological modulation of the tumor microenvironment and its responses to pharmacological intervention as well as the application of nanotechnology to diagnostic, monitoring, and therapeutic purposes are high-priority topics. Studies demonstrating the repositioning of drugs that act on molecular targets of melanoma are also welcome.
Please note: manuscripts consisting solely of bioinformatics, computational analysis, or predictions of public databases which are not accompanied by validation (independent cohort or biological validation in vitro or in vivo) will not be accepted in any of the sections of Frontiers in Oncology.
Keywords: Skin cancer, Melanoma, Immunology, Nanotechnology, Cancer biomarkers, Drug repositining, Immunotherapy
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.