About this Research Topic
This Research Topic will accept manuscripts in the form of Original Research, Review, Methods, and Perspective articles. Studies using cell culture, animal models and human data are all welcomed. We encourage submissions of papers focused on mechanisms of pain at any level from genetic, molecular, anatomical to pharmacological levels, especially pain experience in children. Furthermore, we are interested in manuscripts focusing on mechanisms of clinical strategies to cure pain in children of different ages from neonates to adolescents.
Potential topics include but are not limited to the following:
- Genetic, epigenetic, transcriptional, and translational mechanisms of childhood pain or migraine
- Ion channel, signalling pathway, neuronal excitability, synaptic plasticity, glial cell function, neural circuits in childhood pain or migraine
- Short-term or long-term influences of childhood pain on pain processing, stress responsivity or others
- Experience-induced exaggeration of pain, for example, neonatal pain experience, early-life stress, sleep disorder, repeated surgery or inflammation
- Mechanisms of pharmacological and non-pharmacological treatment for childhood pain or migraine, such as local anesthesia and exercise
- Sex dimorphism in childhood pain or migraine
Keywords: pain, childhood pain, experience, surgery, migraine, mechanisms, therapeutics, ion channel, glia, neuron
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.