Frontiers | Revolutionizing Immunological Disease Understanding Through Single Cell Multi-Omics Technologies

Revolutionizing Immunological Disease Understanding Through Single Cell Multi-Omics Technologies

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ORIGINAL RESEARCH

Published on 14 Jan 2025

Upregulation of interferon-γ response genes in monocytes and T cells identified by single-cell transcriptomics in patients with anti-citrullinated peptide antibody-positive early rheumatoid arthritis

Bong-Ki Hong
Sungyong You
Jung Gon Kim
Minhyung Kim
Naeun Lee
Kijun Lee
In-Pyo Baek
Ji Hyeon Ju
Wan-Uk Kim
Ho-Youn Kim

doi 10.3389/fimmu.2024.1439082

472 views

ORIGINAL RESEARCH

Published on 13 Jan 2025

Single-cell RNA-seq reveals immune cell heterogeneity and increased Th17 cells in human fibrotic skin diseases

Cheng-Cheng Deng
Xue-Yan Xu
Yan Zhang
Long-Can Liu
Xuan Wang
Jun-Yi Chen
Liu-Yi Yao
Ding-Heng Zhu
Bin Yang

doi 10.3389/fimmu.2024.1522076

438 views

REVIEW

Published on 09 Jan 2025

Advancing precision cancer immunotherapy drug development, administration, and response prediction with AI-enabled Raman spectroscopy

Jay Chadokiya
Kai Chang
Saurabh Sharma
Jack Hu
Jennie R. Lill
Jennifer Dionne
Amanda Kirane

doi 10.3389/fimmu.2024.1520860

680 views

ORIGINAL RESEARCH

Published on 30 Oct 2024

A cost-effective protocol for single-cell RNA sequencing of human skin

Saba Khoshbakht
Özgür Albayrak
Ergün Tiryaki
Orhan Ağcaoğlu
Ayşe Öktem
Gizem Pınar Sun
Elif Er Gülbezer
Sümeyre Seda Ertekin
Ayşe Boyvat
1 more
Seçil Vural

doi 10.3389/fimmu.2024.1393017

752 views

ORIGINAL RESEARCH

Published on 19 Jul 2024

Spatial and phenotypic heterogeneity of resident and monocyte-derived macrophages during inflammatory exacerbations leading to pulmonary fibrosis

Philip J. Moos
Jenna R. Cheminant
Sophie Cowman
Jessica Noll
Qiuming Wang
Teresa Musci
Alessandro Venosa

doi 10.3389/fimmu.2024.1425466

2,595 views
1 citation

ORIGINAL RESEARCH

Published on 25 Jun 2024

Using adjusted local assortativity with Molecular Pixelation unveils colocalization of membrane proteins with immunological significance

Jan Rhomberg-Kauert
Max Karlsson
Divya Thiagarajan
Tomasz Kallas
Filip Karlsson
Simon Fredriksson
Johan Dahlberg
Alvaro Martinez Barrio

doi 10.3389/fimmu.2024.1309916

1,357 views

ORIGINAL RESEARCH

Published on 28 Nov 2023

The Simple prEservatioN of Single cElls method for cryopreservation enables the generation of single-cell immune profiles from whole blood

Sarthak Satpathy
Beena E. Thomas
William J. Pilcher
Mojtaba Bakhtiari
Lori A. Ponder
Rafal Pacholczyk
Sampath Prahalad
Swati S. Bhasin
David H. Munn
Manoj K. Bhasin

doi 10.3389/fimmu.2023.1271800

3,157 views
6 citations

ORIGINAL RESEARCH

Published on 20 Nov 2023

Identification of drug candidates targeting monocyte reprogramming in people living with HIV

Rainer Knoll
Lorenzo Bonaguro
Jéssica C. dos Santos
Stefanie Warnat-Herresthal
Maartje C. P. Jacobs-Cleophas
Edda Blümel
Nico Reusch
Arik Horne
Miriam Herbert
12 more
Anna C. Aschenbrenner

doi 10.3389/fimmu.2023.1275136

12,570 views
4 citations

ORIGINAL RESEARCH

Published on 16 Oct 2023

Cell-type-specific molecular characterization of cells from circulation and kidney in IgA nephropathy with nephrotic syndrome

Qilin Chen
Huimin Jiang
Rong Ding
Jinjie Zhong
Longfei Li
Junli Wan
Xiaoqian Feng
Liping Peng
Xia Yang
10 more
Qiu Li

doi 10.3389/fimmu.2023.1231937

4,419 views
2 citations

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Articles

Upregulation of interferon-γ response genes in monocytes and T cells identified by single-cell transcriptomics in patients with anti-citrullinated peptide antibody-positive early rheumatoid arthritis

Single-cell RNA-seq reveals immune cell heterogeneity and increased Th17 cells in human fibrotic skin diseases

Advancing precision cancer immunotherapy drug development, administration, and response prediction with AI-enabled Raman spectroscopy

A cost-effective protocol for single-cell RNA sequencing of human skin

Spatial and phenotypic heterogeneity of resident and monocyte-derived macrophages during inflammatory exacerbations leading to pulmonary fibrosis

Using adjusted local assortativity with Molecular Pixelation unveils colocalization of membrane proteins with immunological significance

The Simple prEservatioN of Single cElls method for cryopreservation enables the generation of single-cell immune profiles from whole blood

Identification of drug candidates targeting monocyte reprogramming in people living with HIV

Cell-type-specific molecular characterization of cells from circulation and kidney in IgA nephropathy with nephrotic syndrome

Frontiers in Immunology

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