About this Research Topic

Background

Saliva is an abundant and easily accessible biofluid that can be collected by non-invasive methods, showing immense promise for monitoring health and disease of the oral cavity and also potentially the rest of the body, in conditions such as periodontitis, caries, cancer and Covid-19. Saliva contains a broad range of molecules that could be used as biomarkers, and many can be discovered by high content ‘omic' approaches. These approaches are essential for the next generation of biomarkers, as it seems likely that combinations of biomarkers will perform better at detecting changes in health than single biomarkers.

The goal of this Research Topic is to explore the biomarkers that are being used to assess health and disease in saliva. Novel approaches in the discovery and detection of saliva biomarkers are welcomed, as well as a wide range of disease types either found or manifested in the mouth. Studies exploring the validation of proposed biomarkers and potential clinical applications of saliva as a diagnostic tool are also of interest.

Articles on the following topics are welcome:

-Discovery of molecules in saliva for detection of health and disease;
-Detection methods for monitoring biomarkers in saliva;
-Biomarkers for oral, and systemic diseases as detected in saliva;
-Biomarkers for monitoring oral treatments (that may not be described as disease but modulate the oral cavity)
-Evaluation of salivary biomarkers
-Clinical application of saliva as a diagnostic tool

Keywords: Salivary Biomarkers, Oral and Systemic Diseases

Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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