About this Research Topic
The editors of this research topic invite all the researchers to submit their original research, and reviews or minireview articles to present and/or summarize the recent advancement on this topic illustrated below, which are for guidance purposes but are not limited to the following:
• HLA antigens, epitope matching, and in solid organ transplantation to prevent transplant rejection and management of immunosuppression
• Assessment of Donor specific anti-HLA antibodies in solid organ transplantation
• HLA matching in hematopoietic stem cell transplantation
• HLA disease association studies
• HLA association with infectious disease
• HLA association studies in cancer immunotherapy, and vaccine design.
• HLA functional studies in human and animal models
• Development of novel experimental methods and approaches for sequencing HLA regions, and resolving ambiguities
• HLA gene editing studies
Manuscripts covering pure bioinformatic analyses are not in the scope of the Immunogenetics section of Frontiers in Genetics. Experimental (wet lab) validation of the in silico obtained results is a prerequisite for peer review. Further, reports oriented towards the application of genetic analyses in oncological disease are not to be primarily targeted to the Immunogenetics unless they evolve in detail around the MHC (HLA) or other major immunogenetic systems and how those affect immune response and or therapy documented by real laboratory and/or clinical data, not solely bioinformatic analyses.
Keywords: personalized medicine, immunology
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.