About this Research Topic
At the same time, several systemic diseases directly or indirectly affect the cardiovascular system and result in vascular injury through mutual underlying mechanisms. From autoimmune rheumatic diseases to novel clinical entities such as coronavirus disease - 19 (COVID-19), the list of systemic diseases associated with vascular injury is constantly growing.
In this complex field, novel hypotheses are generated and several questions remain unanswered. The present Research Topic aims to unravel pathophysiological and clinical aspects of vascular injury in vivo or using animal models, including the development and validation of vascular and circulating biomarkers, and provide further mechanistic and clinical insights on the role of vascular injury with particular emphasis on diagnostics and treatment. In this interdisciplinary field, we welcome basic, translational and clinical researchers from different specialties to provide their input in order to introduce and promote novel concepts and summarize state-of-the-art knowledge.
This Research Topic aims to gather Original Research, Systematic Review, Methods, Review, Mini Review, Policy and Practice Reviews, Hypothesis and Theory, Perspective, Clinical Trial, Case Report, General Commentary, and Opinion articles. Topics may include (but are not limited to) studies on micro- and macrovascular injury, morphology and function under the influence of systemic diseases, such as:
• Cardiovascular diseases (e.g., acute and chronic coronary syndromes, heart failure, hypertension, diabetes mellitus, and chronic kidney disease)
• Autoimmune rheumatic disorders (e.g., rheumatoid arthritis, systemic lupus erythematosus, systemic sclerosis, systemic vasculitis)
• Chronic inflammatory diseases (e.g., psoriasis, inflammatory bowel disease)
• Hematological disorders
• COVID-19 and other infectious diseases
Keywords: vascular injury, cardiovascular disease, hematological disorders, chronic inflammatory diseases, autoimmune rheumatic disorders, COVID-19, infections
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.