About this Research Topic
Despite ongoing research, pulmonary arterial hypertension remains a significant therapeutic challenge. In this research theme, we invite researchers to provide original research or review articles to help explore new factors that contribute to the pathophysiological mechanisms of pulmonary arterial hypertension, and efforts to design and develop new therapeutic opportunities and strategies. Contributions on Group II or III PAH are particularly encouraged.
Subtopics include, but are not limited to:
· The role of metabolic, autophagy, epigenetics, inflammation, fibrosis, etc.in the pathophysiology of PAH.
· Signaling pathways involved in the onset and development of PAH.
· The field in therapeutic strategies to impede or decelerate the progression of PAH.
We strongly encourage research using animal models and human participants, and studies that include hemodynamic data as well as fundamental measures of cell and organ system biology.
Keywords: Pulmonary diseases, pulmonary hypertension, pathophysiology, pathogenesis, diagnosis
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.