About this Research Topic
Personalized medicine allows patients to receive specific therapies that work best for them aiming for more effective treatment, better outcomes, safer clinical managements and more efficient health systems.
The diversity of pharmacological mechanisms and targets can permit therapies to efficiently target particular clinical patients. The integration of expertise from basic molecular research to clinical and diagnostic interventions, including regulatory, ethical and policy aspects is much needed to better understand peculiar patient responses to treatments.
Despite the number of targeted drugs has grown in the last decade, most of the current therapeutic approaches are obtained from large scale studies. Efforts are needed to determine medical treatments that best work for each patient, especially for those unresponsive to traditional treatments. In this regards, knowledge of the targets and the molecular mechanisms that might benefit particular populations is of crucial importance. There is demand for evidence demonstrating the clinical value of personalized treatments once integrated into health systems.
This Research Topic aims to shed a light on the most recent targets, and molecular mechanisms involving precision medicine. It will cover the most recent advances, challenges and future perspectives related to personalized medicine. Integrating expertise from the molecular and translational pharmacology sciences can provide important knowledge on the future therapies that can best impact individual health.
This Research Topic focuses on contributions covering themes not limited to the followings:
- Pharmacology targets for prevention and treatment of diseases
- Personalized biomarkers for future therapeutics
- Application of pharmacogenetics in personalized medicine
- Omics-based studies for precision medicine
- Precision medicine pharmacodynamics
- Precision medicine pharmacokinetics
- In vitro models for personalized medicine
- Integration of nanotechnologies in precision medicine
- Artificial intelligence for personalized intervention
We welcome submission of different article types including Original Research, Reviews, Mini-Reviews, Brief Research Reports, Perspective and Opinion articles.
Please note that:
- If patient data are analyzed, a comprehensive description of the patients including sex, age, diagnostic criteria, inclusion and exclusion criteria, disease stage, therapy received, comorbidities as well as additional clinical information and assessment of clinical response/effects should be included.
- If genetic, proteomics, metabolomics, or other omics data are analyzed, a comprehensive description of the methods and the rationale for the selection of the specific data studied should be provided.
- Studies related to natural compounds, herbal extracts, or traditional medicine products, will not be included in this Research Topic.
Keywords: Precision medicine, Biomarkers, Prevention, Diagnosis, Treatment, Pharmacodynamics, Pharmacokinetics, Medicinal plants, Cancer, COVID-19, Pharmacogenetics, Pharmacological target
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.