About this Research Topic
The current understanding of the immune response to conventional or new-generation vaccines used in animals remains limited, hindering the improvement of their safety and efficacy. Despite numerous reports of the limited efficacy of commercial animal vaccines, the literature on this subject is inadequate, impeding further studies aimed at improving these vaccines. The majority of animal vaccines utilised globally are live-attenuated, which might possess safety concerns or exhibit limited immunogenicity. Additionally, the immune responses to these vaccines are often poorly characterised in hosts, highlighting the need for further investigation and characterisation to improve their safety and efficacy. With recent increases in demand for animal proteins and rates of animal pet adoption, along with the emergence of zoonotic diseases, it is becoming increasingly vital to improve the safety and efficacy of conventional animal vaccines and investigate the development of new-generation vaccines.
Comprehensive research studies on conventional and advanced animal vaccines are necessary to fine-tune their safety and efficacy. However, with the advancement of research technologies and access to advanced research materials for studying the immune response in animals, the gaps in knowledge are being filled. Further, with the increasing demand for animal proteins and the rise of zoonotic diseases, it is becoming increasingly important to prioritize the development of improved animal vaccines to protect animal health, human health, and ensure food security. In light of this, we propose to invite manuscripts that address the characterization of the efficacy and safety of conventional and advanced animal vaccines, aiming to advance the field and pave the way for further improvement of these vaccines.
In this research topic, we are interested to understand the safety and immune response to conventional and new-generation animal vaccines. We welcome the submission of Original Research, Review, Mini Review and perspective articles to cover the following subtopics:
• Immunogenicity/Efficacy and Safety of Live attenuated, Inactivated, Viral-vectored, DNA
and mRNA animal vaccines
• Immune correlates of protection
• Role of adjuvants in enhancing vaccine immunity
• Reverse genetics to enhance the safety and protection of RNA virus vaccines
• Genetic regulation of immune responses to vaccines
• New advances in the vaccine delivery systems
Topic Editor Dr. Mohamed Faizal Abdul-Careem received financial support from UTechnology Ltd. The other Topic Editors declare no competing interests with regard to the Research Topic subject.
Comprehensive research studies on conventional and advanced animal vaccines are necessary to fine-tune their safety and efficacy. However, with the advancement of research technologies and access to advanced research materials for studying the immune response in animals, the gaps in knowledge are being filled. Further, with the increasing demand for animal proteins and the rise of zoonotic diseases, it is becoming increasingly important to prioritize the development of improved animal vaccines to protect animal health, human health, and ensure food security. In light of this, we propose to invite manuscripts that address the characterization of the efficacy and safety of conventional and advanced animal vaccines, aiming to advance the field and pave the way for further improvement of these vaccines.
In this research topic, we are interested to understand the safety and immune response to conventional and new-generation animal vaccines. We welcome the submission of Original Research, Review, Mini Review and perspective articles to cover the following subtopics:
• Immunogenicity/Efficacy and Safety of Live attenuated, Inactivated, Viral-vectored, DNA
and mRNA animal vaccines
• Immune correlates of protection
• Role of adjuvants in enhancing vaccine immunity
• Reverse genetics to enhance the safety and protection of RNA virus vaccines
• Genetic regulation of immune responses to vaccines
• New advances in the vaccine delivery systems
Topic Editor Dr. Mohamed Faizal Abdul-Careem received financial support from UTechnology Ltd. The other Topic Editors declare no competing interests with regard to the Research Topic subject.
Keywords: Vaccines, Animals, Protection, Safety, Efficacy, Immune response, Immunogenicity, Antibodies, Adjuvants, Conventional vaccines, new-generation vaccines
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