About this Research Topic
Diabetes mellitus is a heterogeneous disorder characterized by chronic hyperglycemia. Genetic background plays a key-role in MODY/monogenic diabetes and so-called syndromic diabetes, but to some extent, it also plays a role in the pathogenesis of type 1 and type 2 diabetes.
Diabetes caused by a single gene mutation is an interesting model of precision medicine. In these patients, genetic testing may yield an early diagnosis, support the choice of a specific treatment and follow-up, may reduce the risk of long-term complications, and support the genetic counselling. In addition, psychological and family adjustments may also be improved when the etiological cause of the disease is known. On the other hand, the role of individual susceptibilities in determining type 1 and type 2 diabetes has been highlighted in several papers. The increasing knowledge in this field prompts researchers to run appropriate trials for the prevention of diabetes and its complications.
Contributions from different professions are welcome, and all article types accepted by Frontiers are encouraged. This Research Topic aims to collect high-quality research papers that address genetic issues about diabetes mellitus. In particular, we encourage submission of manuscripts focusing on the benefits of genetic testing, reporting novelties in the knowledge of molecular mechanisms of diabetes, and reviewing state-of-the-art approaches relating to the genetics of diabetes.
Diabetes caused by a single gene mutation is an interesting model of precision medicine. In these patients, genetic testing may yield an early diagnosis, support the choice of a specific treatment and follow-up, may reduce the risk of long-term complications, and support the genetic counselling. In addition, psychological and family adjustments may also be improved when the etiological cause of the disease is known. On the other hand, the role of individual susceptibilities in determining type 1 and type 2 diabetes has been highlighted in several papers. The increasing knowledge in this field prompts researchers to run appropriate trials for the prevention of diabetes and its complications.
Contributions from different professions are welcome, and all article types accepted by Frontiers are encouraged. This Research Topic aims to collect high-quality research papers that address genetic issues about diabetes mellitus. In particular, we encourage submission of manuscripts focusing on the benefits of genetic testing, reporting novelties in the knowledge of molecular mechanisms of diabetes, and reviewing state-of-the-art approaches relating to the genetics of diabetes.
Keywords: Diabetes mellitus, Monogenic diabetes, MODY, Mitochondrial diabetes, Neonatal diabetes, Syndromic diabetes. Pharmacogenomics, Genetics, Prevention, Genetic etiology, Personalized medicine, Precision medicine
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
