About this Research Topic
Chronic disease represents a large and growing burden to the health care system worldwide. It is widely accepted that high consumption of dietary bioactive compounds, especially phytochemicals, is associated with a decreased risk of chronic disease. Dietary bioactive compounds have the potential to treat chronic diseases by reducing oxidative stress, activating inflammatory pathways, and/or reshaping the gut microbiota. However, the underlying mechanism behind these activities and the crosslinks among these pathways are not clear yet. As the nutrigenomics era comes, multidimensional life science omics data with artificial intelligence make it possible to reveal the underlying molecular mechanism and the complex crosslinks between signaling pathways and gut microbiota. Therefore, studies focused on further molecular mechanisms by targeting redox related signaling pathways of chronic diseases and the role of dietary bioactive compounds on chronic disease chemoprevention, as well as the interactions between these pathways and gut microbiota in vitro and in vivo are urgently needed, especially with the aid of multiple omics and AI, which could help us to comprehensively understand the meaning of life and promote a healthier life for ourselves.
The goal of this Research Topic is to provide a forum on the contribution of dietary bioactive compounds on chronic diseases chemoprevention through investigations or systemic reviews on the interactions occurring on the interfaces between dietary bioactive compounds, gut microbiota, and redox related signaling pathways by using advanced omics tools or artificial intelligence technical, both in in vitro and in vivo models.
1. Further molecular mechanisms underlying the chemoprevention of dietary bioactive compounds in chronic diseases
2. Relations between dietary bioactive compounds intake and COVID-19 or COVID-19 plus chronic diseases
3. Gut microbiota-oriented effects of dietary bioactive compounds on chronic diseases
4. Dietary bioactive compounds delivery system and structure modification on chronic disease chemoprevention
5. Effects of phytochemicals or dietary fiber intake on intestinal flora and blood parameters in chronic diseases and new findings in clinical predictors of chronic diseases in patients
6. Nutrigenomics or multiple omics or AI techniques application in chronic disease chemoprevention
The goal of this Research Topic is to provide a forum on the contribution of dietary bioactive compounds on chronic diseases chemoprevention through investigations or systemic reviews on the interactions occurring on the interfaces between dietary bioactive compounds, gut microbiota, and redox related signaling pathways by using advanced omics tools or artificial intelligence technical, both in in vitro and in vivo models.
1. Further molecular mechanisms underlying the chemoprevention of dietary bioactive compounds in chronic diseases
2. Relations between dietary bioactive compounds intake and COVID-19 or COVID-19 plus chronic diseases
3. Gut microbiota-oriented effects of dietary bioactive compounds on chronic diseases
4. Dietary bioactive compounds delivery system and structure modification on chronic disease chemoprevention
5. Effects of phytochemicals or dietary fiber intake on intestinal flora and blood parameters in chronic diseases and new findings in clinical predictors of chronic diseases in patients
6. Nutrigenomics or multiple omics or AI techniques application in chronic disease chemoprevention
Keywords: Dietary bioactive compounds, Chronic disease, nutrigenomics, gut microbiota, omics
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