Frontiers | High-throughput Sequencing-based Investigation of Chronic Disease Markers and Mechanisms, Volume II

High-throughput Sequencing-based Investigation of Chronic Disease Markers and Mechanisms, Volume II

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ORIGINAL RESEARCH

Accepted on 10 Feb 2025

Multi-omics analysis reveals Jianpi formula-derived bioactive peptide-YG-22 potentially inhibited colorectal cancer via regulating epigenetic reprogram and signal pathway regulation

Jun Wang
Lijuan Zhu
Yuan Yuan Li
Mingming Ding
Xiyu Wang
Bo Xiong
Hongyu Chen
Lisheng Chang
Wenli Chen
2 more
Qin Shi

doi 10.3389/fgene.2025.1560172

ORIGINAL RESEARCH

Published on 01 Nov 2024

Bioinformatical analysis and experimental validation of endoplasmic reticulum stress-related biomarker genes in type 2 diabetes mellitus

Lili Yao
Jie Xu
Xu Zhang
Zhuqi Tang
Yuqing Chen
Xiaoyu Liu
Xuchu Duan

doi 10.3389/fgene.2024.1445033

828 views

ORIGINAL RESEARCH

Published on 08 Aug 2024

GWAS-significant loci and severe COVID-19: analysis of associations, link with thromboinflammation syndrome, gene-gene, and gene-environmental interactions

Alexey Valerevich Loktionov
Ksenia Andreevna Kobzeva
Andrey Romanovich Karpenko
Vera Alexeevna Sergeeva
Yuriy Lvovich Orlov
Olga Yurievna Bushueva

doi 10.3389/fgene.2024.1434681

1,016 views
1 citation

BRIEF RESEARCH REPORT

Published on 17 May 2024

Comparative transcriptomics revealed neurodevelopmental impairments and ferroptosis induced by extremely small iron oxide nanoparticles

Zhaojie Lyu
Yao Kou
Yao Fu
Yuxuan Xie
Bo Yang
Hongjie Zhu
Jing Tian

doi 10.3389/fgene.2024.1402771

871 views
1 citation

ORIGINAL RESEARCH

Published on 03 Nov 2023

Integrative transcriptome analysis reveals alternative polyadenylation potentially contributes to GCRV early infection

Sheng Tan
Jie Zhang
Yonglin Peng
Wenfei Du
Jingxuan Yan
Qin Fang

doi 10.3389/fmicb.2023.1269164

1,001 views
1 citation

BRIEF RESEARCH REPORT

Published on 19 Oct 2023

Identification and functional characterization of de novo variant in the SYNGAP1 gene causing intellectual disability

Boxuan Li
Yu Wang
Dong Hou
Zhen Song
Lihua Zhang
Na Li
Ruifang Yang
Ping Sun

doi 10.3389/fgene.2023.1270175

2,073 views

ORIGINAL RESEARCH

Published on 31 Aug 2023

Transcriptome profiling of intact bowel wall reveals that PDE1A and SEMA3D are possible markers with roles in enteric smooth muscle apoptosis, proliferative disorders, and dysautonomia in Crohn’s disease

Yun Yang
Lin Xia
Wenming Yang
Ziqiang Wang
Wenjian Meng
Mingming Zhang
Qin Ma
Junhe Gou
Junjian Wang
1 more
Xiaoting Wu

doi 10.3389/fgene.2023.1194882

1,928 views

ORIGINAL RESEARCH

Published on 27 Jul 2023

Transcriptomic analysis of paired healthy human skeletal muscles to identify modulators of disease severity in DMD

Shirley Nieves-Rodriguez
Florian Barthélémy
Jeremy D. Woods
Emilie D. Douine
Richard T. Wang
Deirdre D. Scripture-Adams
Kevin N. Chesmore
Francesca Galasso
M. Carrie Miceli
Stanley F. Nelson

doi 10.3389/fgene.2023.1216066

3,849 views
1 citation

CASE REPORT

Published on 16 Jun 2023

Case report: Application of targeted NGS for the detection of non-canonical driver variants in MPN

Jin Zhang
Kefeng Shen
Min Xiao
Jinjin Huang
Jin Wang
Yaqin Wang
Zhenya Hong

doi 10.3389/fgene.2023.1198834

2,689 views
1 citation

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Articles

Multi-omics analysis reveals Jianpi formula-derived bioactive peptide-YG-22 potentially inhibited colorectal cancer via regulating epigenetic reprogram and signal pathway regulation

Bioinformatical analysis and experimental validation of endoplasmic reticulum stress-related biomarker genes in type 2 diabetes mellitus

GWAS-significant loci and severe COVID-19: analysis of associations, link with thromboinflammation syndrome, gene-gene, and gene-environmental interactions

Comparative transcriptomics revealed neurodevelopmental impairments and ferroptosis induced by extremely small iron oxide nanoparticles

Integrative transcriptome analysis reveals alternative polyadenylation potentially contributes to GCRV early infection

Identification and functional characterization of de novo variant in the SYNGAP1 gene causing intellectual disability

Transcriptome profiling of intact bowel wall reveals that PDE1A and SEMA3D are possible markers with roles in enteric smooth muscle apoptosis, proliferative disorders, and dysautonomia in Crohn’s disease

Transcriptomic analysis of paired healthy human skeletal muscles to identify modulators of disease severity in DMD

Case report: Application of targeted NGS for the detection of non-canonical driver variants in MPN

Frontiers in Genetics

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