Preventing cardiovascular complications of type 2 diabetes

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About this Research Topic

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Background

Diabetes mellitus is a chronic metabolic disease characterized by elevated blood glucose levels, which severely affects the quality of life and survival of patients. There are approximately 537 million diabetic people globally in 2021 predicted to rise to 783 million by 2045 (IDF Diabetes Atlas 2021).

Despite improvements in glycaemic controls and other advanced therapies, vascular complications remain the leading cause of morbidity and mortality in people with type 2 diabetes (T2D).

Therefore, prevention strategies for cardiovascular complications of T2D must be considered a global health goal in light of the increasing prevalence of the disease and its complications.

This Research Topic aims to explore current approaches and novel insight in the prevention of cardiovascular complications of diabetes. New therapies for diabetes, including treatment strategies and improvements in the management of diabetic complications as well as considerations of dietary interventions and physical activity will be examined. Moreover, progresses in identifying biomarkers for the screening, diagnosis, and prognosis of cardiovascular complications of diabetes through innovative technologies (e.g., omics) will be examined.

We are interested in submissions of Original Research papers and Review articles, including basic research, clinical research, development and application of translational medicine, meta-analyses, commentaries, and reviews.

Potential topics include but are not restricted to:

 Lifestyle and dietary changes in preventing cardiovascular complications of diabetes;

 Clinical results on the impact of physical exercise on cardiovascular complications of diabetes;

 In vitro/in vivo studies to evaluate the effect of drugs and natural molecules on endothelial dysfunction and oxidative stress;

 Clinical evidence on novel preventive approaches;

 New biomarkers to early predict cardiovascular complications;

 Omics technologies with the goal of precision medicine in T2D.

Keywords: Type 2 diabetes, endothelial dysfunction, oxidative stress, cardiovascular complications, lifestyle changes, dietary changes, physical activity, rehabilitative exercise, in vitro studies, clinical evidence, innovative technologies, omics approach

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