About this Research Topic
Despite many efforts in the development of therapies for fibrosis, success has been very limited. Recent advances in single cell omics’ tools are beginning to improve our understanding of the molecular and cellular mechanisms which drive fibrosis and providing new opportunities for more targeted approaches for treatment of fibrosis. The major objective of this series is to advance our understanding of the key molecular and cellular mechanisms, which drive ocular fibrosis. The identity of these pathways may provide novel targets for development of new and effective treatments.
Topics of interest include a) growth factors whose dysregulation contribute to ocular fibrosis; b) the role of various extracellular matrix proteins and their dysregulation in ocular fibrosis; c) the role of inflammatory cells and their mediators in ocular fibrosis; d) the impact of various signaling pathways in ocular fibrosis; e) identification and development of potential targets for treatments of ocular fibrosis; and f) development of strategies to identify new and effective targets for mitigation of ocular fibrosis.
Keywords: Ocular fibrosis, molecular, cellular, treatments
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