About this Research Topic
This Research Topic is part of the Methods and Protocols in Toxicology series. Other titles in the series include:
• Methods and Protocols in Clinical Toxicology: 2023
• Methods and Protocols in Regulatory Toxicology: 2023
•Alternative methods: how to replace animal testing with non-invasive methods in immunotoxicology
Introduction and general guidelines
This series aims to highlight the latest experimental techniques and methods used to investigate fundamental questions in Neurotoxicology research. Review articles or opinions on methodologies or applications including the advantages and limitations of each are welcome. This Topic includes technologies and up-to-date methods which help advance science.
It would be favored if method descriptions orient at the ToxTemps (Krebs et al. ALTEX 2019) for also guiding the use of methods by regulatory agencies.
The contributions to this collection will undergo peer-review. Novelty may vary, but the utility of a method or protocol must be evident. We welcome contributions covering all aspects of Neurotoxicology. Submissions will be handled by the team of Topic Editors in the respective sections.
This Research Topic welcomes:
• Methods: Describing either new or existing methods that are significantly improved or adapted for specific purposes. These manuscripts may include primary (original) data.
• Protocols: Detailed descriptions, including pitfalls and troubleshooting, to benefit those who may evaluate or employ the techniques. The protocols must be proven to work.
• Perspective or General Commentaries on methods and protocols relevant for physiology research.
• Reviews and mini-reviews of topical methods and protocols highlighting the important future directions of the field.
Neurotoxicology guidelines
This Research Topic in Neurotoxicology especially welcomes protocols and methods for New Approach Methods (NAMs) in the field of adult or developmental neurotoxicity including high-content and/or high-throughput methods using in vitro or alternative animal models (including disease models). The articles, when applicable, should have a clear and detailed description of test systems (e.g., cellular composition, brain structure, stability, environment) including their biological relevance and applicability domain, exposure scheme (when and for how long,) and methods (e.g., what endpoint is measured and how, have negative, and positive controls been assessed). Reproducibility and predictive capacity should also accompany the methods description. Quality criteria (rationale and importance for readout and how it can influence the method) and human relevance are strongly encouraged.
• Methods and Protocols in Clinical Toxicology: 2023
• Methods and Protocols in Regulatory Toxicology: 2023
•Alternative methods: how to replace animal testing with non-invasive methods in immunotoxicology
Introduction and general guidelines
This series aims to highlight the latest experimental techniques and methods used to investigate fundamental questions in Neurotoxicology research. Review articles or opinions on methodologies or applications including the advantages and limitations of each are welcome. This Topic includes technologies and up-to-date methods which help advance science.
It would be favored if method descriptions orient at the ToxTemps (Krebs et al. ALTEX 2019) for also guiding the use of methods by regulatory agencies.
The contributions to this collection will undergo peer-review. Novelty may vary, but the utility of a method or protocol must be evident. We welcome contributions covering all aspects of Neurotoxicology. Submissions will be handled by the team of Topic Editors in the respective sections.
This Research Topic welcomes:
• Methods: Describing either new or existing methods that are significantly improved or adapted for specific purposes. These manuscripts may include primary (original) data.
• Protocols: Detailed descriptions, including pitfalls and troubleshooting, to benefit those who may evaluate or employ the techniques. The protocols must be proven to work.
• Perspective or General Commentaries on methods and protocols relevant for physiology research.
• Reviews and mini-reviews of topical methods and protocols highlighting the important future directions of the field.
Neurotoxicology guidelines
This Research Topic in Neurotoxicology especially welcomes protocols and methods for New Approach Methods (NAMs) in the field of adult or developmental neurotoxicity including high-content and/or high-throughput methods using in vitro or alternative animal models (including disease models). The articles, when applicable, should have a clear and detailed description of test systems (e.g., cellular composition, brain structure, stability, environment) including their biological relevance and applicability domain, exposure scheme (when and for how long,) and methods (e.g., what endpoint is measured and how, have negative, and positive controls been assessed). Reproducibility and predictive capacity should also accompany the methods description. Quality criteria (rationale and importance for readout and how it can influence the method) and human relevance are strongly encouraged.
Keywords: #CollectionSeries, Methods, Protocols, Neurotoxicology, New Approach Methods, neurotoxicity
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
