Engineering actinomycetes to produce bioactive agents

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ORIGINAL RESEARCH

Published on 25 Nov 2024

Discovery of thiazostatin D/E using UPLC-HR-MS2-based metabolomics and σ-factor engineering of Actinoplanes sp. SE50/110

Laura Schlüter
Kine Østnes Hansen
Johan Isaksson
Jeanette Hammer Andersen
Espen Holst Hansen
Jörn Kalinowski
Yannik Karl-Heinz Schneider

Discovery of thiazostatin D/E using UPLC-HR-MS2-based metabolomics and σ-factor engineering of Actinoplanes sp. SE50/110

doi 10.3389/fbioe.2024.1497138

344 views

ORIGINAL RESEARCH

Published on 28 Feb 2024

Metabolic engineering of Streptomyces peucetius for biosynthesis of N,N-dimethylated anthracyclines

Mandy B. Hulst
Le Zhang
Helga U. van der Heul
Chao Du
Somayah S. Elsayed
Arina Koroleva
Thadee Grocholski
Dennis P. A. Wander
Mikko Metsä-Ketelä
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Gilles P. van Wezel

Metabolic engineering of Streptomyces peucetius for biosynthesis of N,N-dimethylated anthracyclines

doi 10.3389/fbioe.2024.1363803

2,968 views

ORIGINAL RESEARCH

Published on 01 Feb 2024

Challenging old microbiological treasures for natural compound biosynthesis capacity

Imen Nouioui
Alina Zimmermann
Oliver Hennrich
Shuning Xia
Oona Rössler
Roman Makitrynskyy
Juan Pablo Gomez-Escribano
Gabriele Pötter
Marlen Jando
4 more
Yvonne Mast

Challenging old microbiological treasures for natural compound biosynthesis capacity

doi 10.3389/fbioe.2024.1255151

3,160 views
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Frontiers in Bioengineering and Biotechnology

Synthetic Biology

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