Natural Products and Intestinal Health

The intestine is an important digestive and immune organ of the body, and as the "first line of defense", a healthy intestine is essential for maintaining the health of the body. A variety of factors such as genetics, irrational diet, immune deficiency, drug use, and pathogenic microbial infections can lead to intestinal damage. Numerous studies have shown that the gut is closely associated with the development of many diseases, including metabolic diseases, autoimmune diseases, tumors, and inflammatory diseases. Natural products have been shown to have a wide range of physiological and pharmacological activities. With the increasing emergence of drug-resistant bacteria and the side effects of antibiotics, it is of great importance and value to discover natural products that can effectively maintain intestinal health.

This special issue aims to provide up-to-date information through original and review articles about the protective effects of natural products against intestinal damage caused by various factors (especially pathogenic microorganism infections). To investigate the mechanisms related to the alleviation of intestinal damage by natural products and their bioactive substances. To verify the pharmacological activity of natural products through in vivo and in vitro studies to provide more therapeutic strategies for the treatment of intestinal-related diseases.

Potential topics include, but may not be limited to:

• Molecular mechanisms of natural products protection against intestinal damage
• Enteropathogenic microorganisms infections and nanophytotherapy;
• Correlation of gut microbiota and natural products.
• Pharmacological effects studies of natural products.
• Application of multi-omics data to analyze the protective effect of natural products on the intestinal.
• Investigate the molecular mechanisms of intestinal-pathogenic microorganism interaction by the integration of in vitro and/or in vivo models.