About this Research Topic
This Research Topic aims to host a collection of studies to probe the complex aetiology of the cancer genome. We welcome studies that constructed new models, determined new risk factors, better characterized known factors, verified mechanisms, and provided novel techniques or novel clinical strategies based on genetic signatures of cancers. Authors are highly encouraged to submit original research articles and systematic reviews related to this topic. Research topics may include, but are not limited to:
• Most recent perspectives and developments in cancer epidemiology, including investigations on key factors related to diagnostic, prognostic, or other clinical procedures.
• Comprehensive review of current gene signatures with prognostic, preventive, and predictive value, conventional or novel methods for gene signature prediction, as well as future needs and challenges.
• Models or algorithms for predicting cancer risk, prognosis, recurrence, and other issues with clinical relevance based on the genetic information of patients.
• State-of-the-art approaches or new concepts to improve clinical practices of cancer.
• Identification and validation of functional mechanisms of specific signatures related to cancer risk.
• Discovery of potential prognostic and predictive molecular signatures, or markers linking to new cancer subtypes with specific clinical characteristics.
Please note: manuscripts consisting solely of bioinformatics or computational analysis of public genomic or transcriptomic databases which are not accompanied by validation (independent cohort or biological validation in vitro or in vivo) are out of the scope of this section and will not be accepted as part of this Research Topic.
Keywords: cancer epidemiology, Genetic signature, diagnosis, prognosis, cancer recurrence
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.