About this Research Topic
hiPSC-CMs can be derived from patients carrying mutations causative of cardiovascular diseases and grant unlimited access to human heart cells that can be directly related to patients’ history. Furthermore, hiPSC-CMs might be submitted to different culture conditions and are amenable to manipulations to recapitulate acquired diseases. Besides empowering researchers to understand mechanisms of inherited and acquired diseases, patient-specific hiPSC-CMs may provide clinicians with tools to perform educated therapeutical choices that are the ultimate embodiment of personalized medicine.
Frontiers in Cardiovascular Medicine has organized a research topic on Genetic and Acquired Disease Modeling with hiPSC-derived Cardiomyocytes. Led by experts in the field, this research topic will accept manuscripts on this topic with the aim of providing the reader with a comprehensive overview of the latest developments and applications of hiPSC-technologies to study inherited and acquired diseases with cardiac implications.
Sub-topics include, but are not limited to:
1- Translational and mechanistic research on inherited and acquired arrhythmias
2- Translational and mechanistic research on inherited and acquired cardiomyopathies
3- Personalized medicine
4- Novel multimodal assays using hiPSC-CMs
5- Heart tissue engineering
6- Lab-on-a-chip systems
7- hiPSC-CM maturation
Keywords: hiPSC, tissue engineering, hiPSC-CM, assays, personalized medicine
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.