About this Research Topic
A deep understanding of the molecular pathways that drive myeloid cells reprogramming, a detailed description and identification of the myeloid subsets in oncologic, infectious, autoimmune and metabolic disease as well as it association with patients clinical outcome are essential for the development of new therapeutic approaches. Integrating the previously mentioned with trained immunology concepts open the possibility for the development of next generation immunotherapies. The ultimate goal of this collection is to provide an integration of these data to assess if there are myeloid cells profiles associated with disease onset and development and identify its translational value.
We welcome Original Research, Reviews and Mini-reviews covering:
- Novel macrophages/ neutrophil/ monocytes subsets described in the context of disease.
- Molecular pathways involved in reprogramming (receptors, ligands, transcription factors of relevance).
- Strategies for the application of trained immunity approaches ( potential therapeutic approaches)
Keywords: Macrophages, Monocytes, Neutrophils, Polarization, Reprogramming, Trained immunity
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.