About this Research Topic
Immunometabolism has recently emerged as a key mechanism in regulating immune cell function and virus infection. Immune cell activation not only engages specific metabolic pathways but also rearranges their oxidation-reduction (redox) system, allowing for metabolic reprogramming. Metabolic reprogramming of immune cells is involved in the inhibition of viral infection. Viruses have evolved to employ the host's metabolic system for their survival and proliferation. For example, human immunodeficiency virus type-1 alters T-cell immunometabolism for promoting virus replication.
Immunometabolic crosstalk during viral infection will shed new light on how viruses regulate the intricate immune system via metabolic mechanisms. Future research should look into the crosstalk between immunometabolism and viral infection. Systemic immunometabolism induced by a viral infection will reveal new insights into how immune cells communicate with the organism to execute their diverse antiviral tasks most effectively. Ultimately, a central goal of the field is to apply immunometabolism findings to the discovery of novel antiviral strategies.
This Research Topic will provide the latest updates on the applications of immunometabolic approaches in virology research, including viruses infecting Eukaryotic organisms, bacteria, and archaea. This Research Topic welcomes all types of manuscripts that the Virology section permits (e.g., reviews, original research articles, and opinions) on the application of immunometabolic approaches in virology research. Sub-topics could include, but are not limited to, the applications of immunometabolism for:
1. Immunometabolic analysis of viral infection
2. The influence of host immunometabolism on viral proliferation
3. Elucidation of underlying immunometabolic mechanism of viral pathogenesis
4. Tracking the potential antiviral drugs targets of immunometabolic pathways
Immunometabolic crosstalk during viral infection will shed new light on how viruses regulate the intricate immune system via metabolic mechanisms. Future research should look into the crosstalk between immunometabolism and viral infection. Systemic immunometabolism induced by a viral infection will reveal new insights into how immune cells communicate with the organism to execute their diverse antiviral tasks most effectively. Ultimately, a central goal of the field is to apply immunometabolism findings to the discovery of novel antiviral strategies.
This Research Topic will provide the latest updates on the applications of immunometabolic approaches in virology research, including viruses infecting Eukaryotic organisms, bacteria, and archaea. This Research Topic welcomes all types of manuscripts that the Virology section permits (e.g., reviews, original research articles, and opinions) on the application of immunometabolic approaches in virology research. Sub-topics could include, but are not limited to, the applications of immunometabolism for:
1. Immunometabolic analysis of viral infection
2. The influence of host immunometabolism on viral proliferation
3. Elucidation of underlying immunometabolic mechanism of viral pathogenesis
4. Tracking the potential antiviral drugs targets of immunometabolic pathways
Keywords: Viruses, Metabolomics, immunity, immune cells, Metabolic reprogramming, glycolysis
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
