Challenges in NK Cell Therapeutic Development

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ORIGINAL RESEARCH

Published on 02 Apr 2024

Donor KIR genotype based outcome prediction after allogeneic stem cell transplantation: no land in sight

Johannes Schetelig
Henning Baldauf
Falk Heidenreich
Jorinde D. Hoogenboom
Stephen R. Spellman
Alexander Kulagin
Thomas Schroeder
Henrik Sengeloev
Peter Dreger
19 more
Katharina Fleischhauer

Donor KIR genotype based outcome prediction after allogeneic stem cell transplantation: no land in sight

doi 10.3389/fimmu.2024.1350470

1,621 views
4 citations

REVIEW

Published on 11 Mar 2024

Therapeutic approaches to enhance natural killer cell cytotoxicity

Terran D. Stenger
Jeffrey S. Miller

Therapeutic approaches to enhance natural killer cell cytotoxicity

doi 10.3389/fimmu.2024.1356666

3,431 views
3 citations

ORIGINAL RESEARCH

Published on 12 Jan 2024

Enhanced CT-based radiomics model to predict natural killer cell infiltration and clinical prognosis in non-small cell lung cancer

Xiangzhi Meng
Haijun Xu
Yicheng Liang
Mei Liang
Weijian Song
Boxuan Zhou
Jianwei Shi
Minjun Du
Yushun Gao

Enhanced CT-based radiomics model to predict natural killer cell infiltration and clinical prognosis in non-small cell lung cancer

doi 10.3389/fimmu.2023.1334886

1,472 views
3 citations

ORIGINAL RESEARCH

Published on 15 Dec 2023

Optimizing the cryopreservation and post-thaw recovery of natural killer cells is critical for the success of off-the-shelf platforms

Jennifer N. Saultz
Folashade Otegbeye

Optimizing the cryopreservation and post-thaw recovery of natural killer cells is critical for the success of off-the-shelf platforms

doi 10.3389/fimmu.2023.1304689

4,521 views
1 citation

ORIGINAL RESEARCH

Published on 11 Oct 2023

Preclinical assessment of CAR-NK cell-mediated killing efficacy and pharmacokinetics in a rapid zebrafish xenograft model of metastatic breast cancer

Nivedha Murali Shankar
Paola Ortiz-Montero
Anastasia Kurzyukova
Wiebke Rackwitz
Stephan R. Künzel
Winfried S. Wels
Torsten Tonn
Franziska Knopf
Jiri Eitler

Preclinical assessment of CAR-NK cell-mediated killing efficacy and pharmacokinetics in a rapid zebrafish xenograft model of metastatic breast cancer

doi 10.3389/fimmu.2023.1254821

3,712 views
5 citations

ORIGINAL RESEARCH

Published on 28 Sep 2023

Cytokines impact natural killer cell phenotype and functionality against glioblastoma in vitro

Minna Sivonen
Katja A. Sirviö
Sara Wojciechowski
Anssi Kailaanmäki
Satu Kaipainen
Aubrey Bailey
Martin Villalba
Tuija Kekarainen

Cytokines impact natural killer cell phenotype and functionality against glioblastoma in vitro

doi 10.3389/fimmu.2023.1227064

3,270 views
3 citations

ORIGINAL RESEARCH

Published on 25 Sep 2023

Engineering NK-CAR.19 cells with the IL-15/IL-15Rα complex improved proliferation and anti-tumor effect in vivo

Renata Nacasaki Silvestre
Jiri Eitler
Julia Teixeira Cottas de Azevedo
Mariane Cariati Tirapelle
Daianne Maciely Carvalho Fantacini
Lucas Eduardo Botelho de Souza
Kamilla Swiech
Dimas Tadeu Covas
Rodrigo T. Calado
4 more
Virginia Picanço-Castro

Engineering NK-CAR.19 cells with the IL-15/IL-15Rα complex improved proliferation and anti-tumor effect in vivo

doi 10.3389/fimmu.2023.1226518

6,492 views
9 citations

REVIEW

Published on 09 Aug 2023

Natural Killer Cell Engagers (NKCEs): a new frontier in cancer immunotherapy

Minchuan Zhang
Kong-Peng Lam
Shengli Xu

Natural Killer Cell Engagers (NKCEs): a new frontier in cancer immunotherapy

doi 10.3389/fimmu.2023.1207276

12,335 views
16 citations

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Frontiers in Immunology

Frontiers in Immunology

NK and Innate Lymphoid Cell Biology

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