About this Research Topic
Modern society depends on research and the advancement of science to achieve health and prosperity for all. However, to build on already successful science, we encompass the need to discuss the current challenges and issues faced.
Frontiers recognizes the importance of facilitating debate and discussion amongst the community, and so has organized a series of Research Topics, offering a platform for such discussion to occur.
Regenerative Dentistry aims to advance the understanding of tooth development, replacement and repair to result in novel, biological-based therapies in dentistry. Dentistry is uniquely placed to provide and test current and future paradigms in tissue regeneration. With the goals of the field in mind, this Research Topic wishes to foster debate and discussion in the community by sparking discussion around the following topics:
• Tooth development - what is left that we don't already know?
• Regeneration of dental-oral-craniofacial tissues in vitro: methods and applications. Are they translatable to in vivo applications?
• Tooth/tissue regeneration and repair:
a. Current & future approaches: What do you feel is working and why, and where do you see the most promise for future therapies to include but not limited to factors (biologics and synthetics), cell therapies, cell-free therapies, and gene therapies.
b. What are the barriers in moving regenerative therapies from the research side, with evidence for success in regeneration in in vitro and animal models, into clinical trials and then, implementation/adaptation by the clinical community?
c. Are there any predictable regenerative therapies for regeneration of teeth and/or periodontal tissues and/or salivary glands?
• Are there specific tools and technologies we need to be promoting and developing at the research level and the clinical level?
• Are there specific methods, approaches, communication we should implement to have better collaborative efforts across systems focused on regeneration vs duplicative efforts?
• What are the economic aspects for the patient and for the clinician related to regenerative therapies vs other approaches e.g. implants?
This collection is primarily a home for opinion and perspective articles, however this Research Topic also welcomes original research and review articles on the above themes.
Frontiers recognizes the importance of facilitating debate and discussion amongst the community, and so has organized a series of Research Topics, offering a platform for such discussion to occur.
Regenerative Dentistry aims to advance the understanding of tooth development, replacement and repair to result in novel, biological-based therapies in dentistry. Dentistry is uniquely placed to provide and test current and future paradigms in tissue regeneration. With the goals of the field in mind, this Research Topic wishes to foster debate and discussion in the community by sparking discussion around the following topics:
• Tooth development - what is left that we don't already know?
• Regeneration of dental-oral-craniofacial tissues in vitro: methods and applications. Are they translatable to in vivo applications?
• Tooth/tissue regeneration and repair:
a. Current & future approaches: What do you feel is working and why, and where do you see the most promise for future therapies to include but not limited to factors (biologics and synthetics), cell therapies, cell-free therapies, and gene therapies.
b. What are the barriers in moving regenerative therapies from the research side, with evidence for success in regeneration in in vitro and animal models, into clinical trials and then, implementation/adaptation by the clinical community?
c. Are there any predictable regenerative therapies for regeneration of teeth and/or periodontal tissues and/or salivary glands?
• Are there specific tools and technologies we need to be promoting and developing at the research level and the clinical level?
• Are there specific methods, approaches, communication we should implement to have better collaborative efforts across systems focused on regeneration vs duplicative efforts?
• What are the economic aspects for the patient and for the clinician related to regenerative therapies vs other approaches e.g. implants?
This collection is primarily a home for opinion and perspective articles, however this Research Topic also welcomes original research and review articles on the above themes.
Keywords: Regenerative Dentistry, Tooth development, tooth regeneration, dental-oral-craniofacial tissues, #CollectionSeries
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
