Celebrating the Year of Ramon y Cajal: Cellular Biology of the Retina

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About this Research Topic

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Background

The year 2022 has been declared by Pedro Sanchez, President of Spain, as the Year of Ramon y Cajal on the 170th anniversary of his birth. Frontiers in Cellular Neuroscience is celebrating it by hosting a series of Research Topics to present the progress made in the different areas where his discoveries established the ground foundation of modern neuroscience.

The Spanish scientist Dr. Santiago Ramón y Cajal was an indefatigable and accomplished anatomist and a pioneer in the neuroscience field, whose ideas founded many concepts of modern neuroscience. He was the first to advocate the idea of the contiguity of individual cells as the basic unit of the nervous system. Additionally, Ramón y Cajal’s anatomical drawings on the structure of the nervous system still populate textbooks. Ramon y Cajal was especially fascinated by the complexity of the retina. In his publication “The Retina of the Vertebrates” published in 1893, he described the retina as a “true nervous center, a peripheral extension of the CNS (central nervous system)”, and how its structure helped him to understand the organization and basic principles of the CNS providing the foundation of the neuron doctrine and the “dynamic polarization“ theory.

Dr. Santiago Ramon y Cajal and the Italian scientist Dr. Camilo Golgi were awarded the Nobel Prize 1906 in Physiology and Medicine to recognize their work on the structure of the nervous system.

This Research Topic within the “Celebrating the Year of Ramon y Cajal” series, will pay tribute to his work by collecting recent advances in the study of retinal cellular biology and the latest methods applied to better study this complex system. To this end, this Research Topic seeks Original Research, Review, Mini-Review, Hypothesis and Theory, Perspective, Clinical Trial, Case Report, and Opinion articles that cover, but are not limited to, the following topics:

1. Retinal cell biology
2. Retinal molecular biology
3. Retinal genetics
4. Retinal therapeutic strategies
5. Animal models of retinal diseases
6. Stem cell-based models applied to retinal biology and disease
7. RPE biology and disease
8. Retinal vasculature biology and disease
9. Muller cells and retinal microglia
10. Retinal degenerative diseases

Keywords: retinal disease, vascular retina, muller cells, retinal degeneration, retina

Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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