About this Research Topic
This is a Research Topic initiated by NAVBO, the North American Vascular Biology Organization.
Despite the development of potent drugs for modifiable risk factors, such as statins, and advances in mechanistic biomedical research, vascular disease remains the No.1 killer globally. The underlying mechanisms remain incompletely understood and effective new therapies are needed. Accumulating evidence for the disease heterogeneity at cellular and population levels also represents the challenges in vascular medicine. Such major challenges have promoted technological innovations and their implementations in vascular research. Unmet clinical needs and exponential technological development have synergistically advanced vascular medicine. We realize addressing clinical needs requires the accumulation of cross-disciplinary understandings of vascular diseases. This Research Topic thus focuses on new trends in a wide range of vascular medicine research from fundamental basic science to translational medicine to clinical studies. We welcome three types of contributions from various disciplines: 1) review articles; 2) original reports, and 3) papers on new methods. We will cover various topics, including, but not limited to:
• Angiogenesis
• Artificial intelligence/machine learning
• Aortic valve disease/ aortic stenosis
•Arterial diseases
• AV fistula
• AV malformations
• Atherosclerosis
• Blood brain barrier
• Calcification
• Cell-cell interactions
• Computational approaches
• COVID-19
• CNS vascular disease
• Drug discovery
• Dyslipidemia
• Electronic medical records
• Epigenetic regulation
• Extracellular matrix
• Extracellular vesicles
• Gene editing
• Gene therapy
• HIV
• Hypoxia
• Imaging
• Leukocyte
• Lipoproteins
• Lymphangiogenesis/lymphatics
• Macrophages
• Mechanotransduction
• Metabolic disease
• Neurovascular crosstalk
• Ocular vascular disease
• Organ crosstalk
• RNA biology
• RNA therapeutics
• Regenerative medicine
• Signaling in vascular disease
• Smooth muscle cells
• Stem cells
• Systems biology/network medicine
• Target discovery
• Transendothelial migration
• Vaccines
• Vascular aging
• Vascular cell-blood interaction
• Vascular cell-matrix interactions
• Vascular development
• Vascular differentiation
• Vascular malformations
• Vascular plasticity
• Vascular heterogeneity
• Vascular inflammation
• Vein grafts
• Venous Diseases
Despite the development of potent drugs for modifiable risk factors, such as statins, and advances in mechanistic biomedical research, vascular disease remains the No.1 killer globally. The underlying mechanisms remain incompletely understood and effective new therapies are needed. Accumulating evidence for the disease heterogeneity at cellular and population levels also represents the challenges in vascular medicine. Such major challenges have promoted technological innovations and their implementations in vascular research. Unmet clinical needs and exponential technological development have synergistically advanced vascular medicine. We realize addressing clinical needs requires the accumulation of cross-disciplinary understandings of vascular diseases. This Research Topic thus focuses on new trends in a wide range of vascular medicine research from fundamental basic science to translational medicine to clinical studies. We welcome three types of contributions from various disciplines: 1) review articles; 2) original reports, and 3) papers on new methods. We will cover various topics, including, but not limited to:
• Angiogenesis
• Artificial intelligence/machine learning
• Aortic valve disease/ aortic stenosis
•Arterial diseases
• AV fistula
• AV malformations
• Atherosclerosis
• Blood brain barrier
• Calcification
• Cell-cell interactions
• Computational approaches
• COVID-19
• CNS vascular disease
• Drug discovery
• Dyslipidemia
• Electronic medical records
• Epigenetic regulation
• Extracellular matrix
• Extracellular vesicles
• Gene editing
• Gene therapy
• HIV
• Hypoxia
• Imaging
• Leukocyte
• Lipoproteins
• Lymphangiogenesis/lymphatics
• Macrophages
• Mechanotransduction
• Metabolic disease
• Neurovascular crosstalk
• Ocular vascular disease
• Organ crosstalk
• RNA biology
• RNA therapeutics
• Regenerative medicine
• Signaling in vascular disease
• Smooth muscle cells
• Stem cells
• Systems biology/network medicine
• Target discovery
• Transendothelial migration
• Vaccines
• Vascular aging
• Vascular cell-blood interaction
• Vascular cell-matrix interactions
• Vascular development
• Vascular differentiation
• Vascular malformations
• Vascular plasticity
• Vascular heterogeneity
• Vascular inflammation
• Vein grafts
• Venous Diseases
Keywords: cardiovascular medicine, vascular biology, inflammation, endothelial cells, smooth muscle cells, macrophages, T cells, development, cancer, lymphatic vessels, dyslipedemia, systems biology, drug discovery, atherosclerosis, Society Affiliation RT
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
