Reactive Oxygen Species (ROS): The Key Role of Natural Products in Cancer Therapy

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BRIEF RESEARCH REPORT

Published on 29 May 2023

The pro-tumorigenic cytokine IL-32 has a high turnover in multiple myeloma cells due to proteolysis regulated by oxygen-sensing cysteine dioxygenase and deubiquitinating enzymes

Martin Kastnes
Kristin Roseth Aass
Siri Anshushaug Bouma
Charlotte Årseth
Muhammad Zahoor
Mariia Yurchenko
Therese Standal

The pro-tumorigenic cytokine IL-32 has a high turnover in multiple myeloma cells due to proteolysis regulated by oxygen-sensing cysteine dioxygenase and deubiquitinating enzymes

doi 10.3389/fonc.2023.1197542

1,966 views
3 citations

ORIGINAL RESEARCH

Published on 15 May 2023

Dihydromyricetin functions as a tumor suppressor in hepatoblastoma by regulating SOD1/ROS pathway

Tong Guo
Xitong Wang
Gensheng Zhang
Tian Xia
Runzhi Zhu
Jinfa Tou

Dihydromyricetin functions as a tumor suppressor in hepatoblastoma by regulating SOD1/ROS pathway

doi 10.3389/fonc.2023.1160548

1,455 views
6 citations

ORIGINAL RESEARCH

Published on 09 May 2023

Preclinical investigations of the efficacy of the glutaminase inhibitor CB-839 alone and in combinations in chronic lymphocytic leukemia

Natalia Timofeeva
Mary L. Ayres
Natalia Baran
Janice M. Santiago-O’Farrill
Gamze Bildik
Zhen Lu
Marina Konopleva
Varsha Gandhi

Preclinical investigations of the efficacy of the glutaminase inhibitor CB-839 alone and in combinations in chronic lymphocytic leukemia

doi 10.3389/fonc.2023.1161254

3,738 views
10 citations

ORIGINAL RESEARCH

Published on 06 Mar 2023

Platycodin-D exerts its anti-cancer effect by promoting c-Myc protein ubiquitination and degradation in gastric cancer

Qianqian Xu
Guangzhao Pan
Zhonglan Wang
Lingling Wang
Yancheng Tang
Jinyun Dong
Jiang-Jiang Qin

Platycodin-D exerts its anti-cancer effect by promoting c-Myc protein ubiquitination and degradation in gastric cancer

doi 10.3389/fphar.2023.1138658

1,853 views
7 citations

ORIGINAL RESEARCH

Published on 16 Feb 2023

Crebanine induces ROS-dependent apoptosis in human hepatocellular carcinoma cells via the AKT/FoxO3a signaling pathway

Jiajie Tan
Yuling Xiang
Yuanguo Xiong
Yaoyuan Zhang
Boyang Qiao
Hong Zhang

Crebanine induces ROS-dependent apoptosis in human hepatocellular carcinoma cells via the AKT/FoxO3a signaling pathway

doi 10.3389/fphar.2023.1069093

2,275 views
8 citations

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Frontiers in Oncology

Pharmacology of Anti-Cancer Drugs

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Frontiers in Pharmacology
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