About this Research Topic
These days, kidney disease has been demonstrated to be an inflammatory disease, and the roles of pro-inflammatory mediators and anti-inflammatory mechanisms have been discovered with previously unrecognized protective roles in renal disease.
Gut microbiota has been referred as the second gene pool of the human body, and its metabolites play a pivotal role in renal physiology and pathology through the activation of the gut-kidney axis. However, the relationship between gut microbiota and kidney disease remains to be elucidated. Studies in recent decades have confirmed that gut microbiota-derived inflammation might be a novel mechanism in renal physiology and pathology, but the details remain to be further revealed.
Given these main objectives, this Research Topic includes, but is by no means limited to the following subtopics:
• the relationship between inflammation and kidney disease;
• the relationship between gut microbiota and kidney disease;
• the role of inflammation and(or) gut microbiota in renal biochemical and molecular pathways;
• the potential medicine in the prevention of acute and chronic kidney disease with emphasis on inflammation and(or) gut microbiota and other important molecular pathways;
• the association of inflammation and(or) gut microbiota with complications of renal diseases.
Keywords: inflammation, renal disease, gut microbiota, mechanisms
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